Results 191 to 200 of about 201,589 (345)

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Reprogrammable All‐Photonic Molecular Logic With Ln3+ Luminescent Hybrids in Solid State

open access: yesLaser &Photonics Reviews, EarlyView.
Mario P. de‐Saralegui et al. report an Eu3⁺/Tb3⁺‐doped organic–inorganic hybrid material that enables multiple reprogrammable logic operations using only physical stimuli. Additionally, this solid‐state, all‐photonic platform represents the first example in the literature performing reversible Feynman logic operations, marking a major step toward ...
Mario P. de‐Saralegui   +4 more
wiley   +1 more source

Curcumin inhibits glycolysis via EP300 in oral squamous cell carcinoma. [PDF]

open access: yesSci Rep
Tan W   +8 more
europepmc   +1 more source

Predictive Modelling of Solvent Effects on Drug Incorporation into Polymeric Nanocarriers: A Machine Learning Approach

open access: yesMacromolecular Rapid Communications, EarlyView.
When seeking nanoparticles with elevated drug loading content, the experimental setup, including solvent selection, is crucial. Through machine learning, we pinpointed that the drug's solubility in the organic solvent is the key factor for attaining high drug loading content.
Wei Ge   +4 more
wiley   +1 more source

Poly(2‐Oxazoline)‐Based Polyphotoacids: Synthesis, Solution Behavior, and Cellular Uptake of Multi‐Responsive Intracellular Transporters

open access: yesMacromolecular Rapid Communications, EarlyView.
The ability of photoacids to increase their acidity in response to light irradiation (excited state proton transfer, ESPT) makes them attractive building blocks for the design of stimuli‐responsive copolymers. In this contribution, we present highly biocompatible polyphotoacids based on poly(2‐oxazoline)s bearing 1‐hydroxypyrene units. Low cytotoxicity,
Leonid I. Kaberov   +7 more
wiley   +1 more source

Modulation of the stress-activated protein kinases Hog1/p38 and a TORC1-dependent kinase by curcumin is stress granule-dependent. [PDF]

open access: yesJ Biol Chem
Zheng L   +8 more
europepmc   +1 more source

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