Results 131 to 140 of about 491,441 (311)

New addition curing polyimides [PDF]

open access: yes
In an attempt to improve the thermal-oxidative stability (TOS) of PMR-type polymers, the use of 1,4-phenylenebis (phenylmaleic anhydride) PPMA, was evaluated.
Cavano, Paul, Frimer, Aryeh A.
core   +1 more source

Titanium reinforced boron polyimide composite [PDF]

open access: yes, 1972
Program involves development of process technique for boron-polyimide prepeg, lay-up and curing procedures for prepegs when processed under vacuum bag pressure, and development and evaluation of titanium hard points for smooth transition of loads from ...
Clark, G. A.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Additive manufacturing of silicone for biomedical applications

open access: yesBiomedical Engineering Advances
The manufacturing of silicone-based elastomers has been the center of research for several decades and the renaissance of the manufacturing industry via additive manufacturing (AM) seems to verve the hype of the widespread industrial applications of ...
Deon Johan de Beer   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Development of improved semi-organic structural adhesives for elevated temperature applications Technical summary report, 1 ~JUL. 1964 - 29 ~FEB. 1968 [PDF]

open access: yes
Titanium chelate polymer adhesive formulation for aluminum joint curing in high temperature ...
Kwan, S. C.   +5 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Lower-curing-temperature PMR polyimides [PDF]

open access: yes
Partial substitution of a p-aminostyrene end-cap for the monomethyl ester of 5-norbornene-2, 3-dicarboxylic acid lowered the final cure temperature of typical PMR resins from 600 F to 500 F.
Delvigs, P.
core   +1 more source

Talking Cure and Curing Talk [PDF]

open access: yesJournal of the Royal Society of Medicine, 2005
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

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