Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Estimation of corrosion resistance of curing mixtures based on coal-bearing rocks from Western Donbass [PDF]
, 2016 Purpose. Substantiation of possible use of coal-bearing rocks as a replacement for a part of the filler in the preparation of shotcrete for lining of mine workings in the conditions of mineralized mine water. Methods.
Harkusha, V, Kovalenko, V
core +2 more sources
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Technique for the polymerization of monomers for PPQ/graphite fiber composites [PDF]
, 1973 Impregnation of fiber prior to appreciable polymerization completely eliminates impregnation problems encountered with use of high viscosity high molecular weight polyphenylquinoxalines (PPQ) solutions. Major part of polymerization of reactant mixture is
Delvigs, P. +2 more
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Depth sensing indentation of organic-inorganic hybrid coatings deposited onto a polymeric substrate [PDF]
, 2012 PEO-Si/SiO2 hybrid coatings deposited onto a PVC substrate were micromechanically characterized using depth sensing indentation. The effect of curing time and coating thickness was investigated.
Fasce, Laura Alejandra +2 more
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
An Address ON THE PRESENT EVIDENCE FOR AND AGAINST THE USE OF TUBERCULIN AS A SPECIFIC CURE: Delivered at a Combined Meeting of the City Division of the British Medical Association and the Finsbury Medical Society [PDF]
, 1913 H. B. Shaw
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Titanium reinforced boron polyimide composite [PDF]
, 1972 Program involves development of process technique for boron-polyimide prepeg, lay-up and curing procedures for prepegs when processed under vacuum bag pressure, and development and evaluation of titanium hard points for smooth transition of loads from ...
Clark, G. A.
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, 2011 In this dissertation we study several problems related to the management of healthcare and the cure of disease. In each chapter a hospital capacity distribution problem is analyzed using techniques from operations research, also known as mathematical decision theory.
openaire +4 more sources