Results 141 to 150 of about 15,823,108 (321)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Influence of post-fire recuring regimes on the properties of self-compacting concrete with heavyweight aggregate

open access: yesScientific Reports
Fire safety is essential in construction, as accidental fires subject concrete structures to high temperatures that result in significant damage.
Taher A. Tawfik   +7 more
doaj   +1 more source

EFFECT OF CURING METHOD AND CURING PERIOD ON CHARACTERISTIC OF COMPRESSIVE STRENGTH FOR Ca CONCRETE

open access: yesCement Science and Concrete Technology, 2009
SHIMABUKURO, Atsushi   +1 more
openaire   +2 more sources

UV LED Curing for Silicone Hydrogel Contact Lenses: Breakthrough in Curing Properties and Cosmetic Characteristics

open access: yesPolymers
Ultraviolet light-emitting diode (UV LED) technology offers advantages over conventional UV mercury (UV Hg) lamps, including precise wavelength control, high energy efficiency and rapid curing. While UV LED is widely applied in sectors like dentistry, printing, and electronics, its application in contact lens manufacturing remains relatively low.
Saravanan Nanda Kumar   +5 more
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Experimental Study on Strength and Microstructure of Loess Improved by CG-2 Curing Agent and Cement

open access: yesBuildings
In order to study the improvement effect of the CG-2 curing agent and cement on loess, a series of physical and mechanical property tests and microstructure tests were carried out on loess improved with different dosages of curing agent and cement to ...
Xuening Ma   +4 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

What are Future Curing Lights Technology Trends?

open access: yes, 2010
Over the recent years, dental curing lights as well as light-cured materials have been undergoing rapid development, which makes choosing a curing light guaranteeing the optimal polymerization degree difficult.
D. Houšová   +3 more
core  

Influence of Curing-light Unit and Exposure Conditions on the Properties of Lightcured Resin Composite on Curing-light Units [PDF]

open access: yes, 2003
P(論文)The purpose of this study was to examine the influence of curing light units and exposure conditions on the prperties of the polymerization of a lightcured resin composite. Lightfil was used as a resin composite.
岡田, 英俊   +23 more
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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