Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Data on the evolution of curing characteristics and properties during the room-temperature annealing process in SSBR/BR gums and SSBR/BR/SiO2 composites. [PDF]
Data Brief, 2019 Zhang X, Cai L, Wang C, He A.
europepmc +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
An Evaluation of the ICON® Mask Fixation: Curing Characteristics of the Thermoplastic Fixation and Implications for Patient Workflow. [PDF]
Radiol Oncol, 2018 Prasad S +3 more
europepmc +1 more source
Vulcanization Characteristics and Curing Kinetics of Rubber-Organoclay Nanocomposites
, 2011 Peer ...
R. Verdejo +4 more
openaire +2 more sources
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
On the Effects of 3D Printed Mold Material, Curing Temperature, and Duration on Polydimethylsiloxane (PDMS) Curing Characteristics for Lab-on-a-Chip Applications. [PDF]
Micromachines (Basel)Mercimek R +7 more
europepmc +1 more source
Real-time synchronous measurement of curing characteristics and polymerization stress in bone cements with a cantilever-beam based instrument. [PDF]
Rev Sci Instrum, 2018 Palagummi SV, Landis FA, Chiang MYM.
europepmc +1 more source