Results 131 to 140 of about 959,172 (357)
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Can Financial Openness Help Avoid Currency Crises? [PDF]
By introducing the concept of conditional probability of joint failure (CPJF), and by proposing a new measure for the systemic impact of currency crises, we provide new insights into the different sources of currency crises.
Garita, Gus, Zhou, Chen
core +1 more source
Exchange rate of Malaysian Ringgit (MYR) forecasting using decomposition method [PDF]
, 2020 The Malaysian Ringgit (MYR) foreign exchange rate has fallen to the lowest level since the 2008 global credit crisis [1]. Hence, the selection of countries for three selected continents in the world has been conducted to study their currency exchange ...
Ahmad Nordin, Norain +4 more
core
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Estimating the Value of Derham and Dinar in Muslims' Economic History [PDF]
فصلنامه پژوهشهای اقتصادی ایران, 2005 Before the appearance of Islam, Dinar and Derham were the currencies of Byzantine and Iran, recpectively. These two currencies were current in pre-Islamic Arabia and continued to be the currencies of primary Islamic states.
Mansour Zarra Nezhad
doaj
Does the currency regime shape unhedged currency exposure. [PDF]
This paper examines how unhedged currency exposure of firms varies with changes in currency flexibility. A sequence of four time- periods with alternating high and low currency volatility in India provides a natural experiment in which changes in ...
Patnaik, Ila, Shah, Ajay
core
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
THE CURRENCY DENOMINATION OF SOVEREIGN DEBT [PDF]
This paper considers the currency composition of sovereign debt in the context of risk-sharing through excusable defaults. It is shown that monetary credibility is not a sufficient condition for borrowing in domestic currency.
Michael Bleaney
core
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source