Results 131 to 140 of about 83,249 (315)
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Multidrug-resistant Opportunistic and Pathogenic Bacteria Contaminate Algerian Banknotes Currency [PDF]
Polish Journal of Microbiology, 2020 LYDIA NEÏLA DJOUADI +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Dollar Damage Awards to Foreign Plaintiffs: Conversion and Revaluation of Foreign Currencies [PDF]
, 1952 openalex +1 more source
THE HEALTHY CURRENCY – AN ALTERNATIVE TO STABLE CURRENCY
CES Working Papers, 2014 In the current historical and economic context of the globalised world, sensitive to fluctuations and liable to economic crisis, we find it especially important to analyse the concept of monetary stability. The purpose of this paper is to critically analyse the concept of monetary stability, from the merchandise-currency point of view as well as ...
Iavorschi, Mihaela, Gradinaru, Andreea
openaire +2 more sources
The commodity currency puzzle [PDF]
, 2005 Abstract: This paper addresses the purchasing power parity (PPP) puzzle for commodity currencies. A substantial part of the literature on commodity currencies has found that, despite controlling for the effect of commodity prices, PPP does not hold in the long run.
Hilde C. Bjørnland, Håvard Hungnes
openaire +4 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source