Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Additomultiplicative Cascades Govern Multifractal Scaling Reliability Across Cardiac, Financial, and Climate Systems. [PDF]
Mangalam M, Watanabe E, Kiyono K.
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Exploring nurse staffing and policy implications in times of crisis: the case of North Lebanon. [PDF]
Dankar MJ, Yazbik-Dumit N, Ammar W.
europepmc +1 more source
Insuring Against Past Perils: The Politics of Post-Currency Crisis Foreign Exchange Reserve Accumulation [PDF]
Liam F. Beiser‐McGrath
openalex +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Sustaining research in crisis settings: the Lebanese experience. [PDF]
Yehya A, Abou-Kheir W.
europepmc +1 more source
Interpreting Currency Movements During the Crisis: What's the Role of Interest Rate Differentials?
Thomas Dowling +3 more
openalex +2 more sources

