Impact of compounded financial collapse and armed conflict on access to radiation therapy in Lebanon: lessons for building resilient cancer care systems in fragile settings. [PDF]
Front OncolSamaha Jabbour C +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Political contagion in currency crises: A comment [PDF]
Comments on: Alan Drazen, whose paper represents a first effort to formalize the role of political considerations in the process of how currency crises are transmitted across international borders. The theoretical literature on “contagion” is scarce, and
Reinhart, Carmen
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
TOWARDS A NEW SET OF LEADING INDICATORS OF CURRENCY CRISIS FOR DEVELOPING COUNTRIES: AN APPLICATION TO ARGENTINA [PDF]
Currency and financial crises are determinants of growth and development, mainly in developing countries subject to shocks, contagion and volatility.
Federico Marongiu
core
Bridging crisis recovery and long-term transformation of the health system in Lebanon: evidence from key informant interviews and global lessons. [PDF]
BMC Health Serv ResKhalife J +6 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
High Frequency Contagion of Currency Crises in Asia [PDF]
Using daily data during the period of Asian Currency Crises, this paper examines high-frequency contagion effects among Asian six countries. By identifying the origin' (of exchange rate depreciation, or decline in stock prices) and the affected ...
Takatoshi Ito, Yuko Hashimoto
core
Cost of emergency hospital admissions to acute general wards for mental health problems among children and young people in England, 2012-2022: a retrospective observational study. [PDF]
BMJ OpenPilvar H +11 more
europepmc +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source