Results 121 to 130 of about 4,437,774 (316)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Multifunctional Fluorescent Probe for Simultaneous Detection of ATP, Cys, Hcy, and GSH: Advancing Insights into Epilepsy and Liver Injury

open access: yesAdvanced Science
Adenosine triphosphate (ATP) is a critical intracellular energy currency that plays a key role in various cellular processes and is closely associated with numerous diseases.
Ting Yu   +9 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

An interpretable model for large-scale smart contract vulnerability detection

open access: yesBlockchain: Research and Applications
Smart contracts hold billions of dollars in digital currency, and their security vulnerabilities have drawn a lot of attention in recent years. Traditional methods for detecting smart contract vulnerabilities rely primarily on symbol execution, which ...
Xia Feng   +4 more
doaj   +1 more source

Currency Detection App for Visually impaired

open access: yes, 2023
Apart from the immediate use of Master cards and any form of electronic payment methods, money has been widely used for general exchange due to its usefulness. However, visually impaired people can suffer to know each currency paper separately. This research project aims to develop a mobile application based on the Convolutional Neutral Network using ...
openaire   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Beyond the p < 0.05 trap: the adaptive integrity model for preventing and detecting P-hacking

open access: yesFrontiers in Education
When statistical significance becomes the currency of publication, the incentive to reach p < 0.05 can subtly shape research behavior. While many researchers report their findings with integrity, others face implicit pressures that increase the ...
Don A. Affognon
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Modern Trends and Recent Applications of Hyperspectral Imaging: A Review

open access: yesTechnologies
Hyperspectral imaging (HSI) is an advanced imaging technique that captures detailed spectral information across multiple fields. This review explores its applications in counterfeit detection, remote sensing, agriculture, medical imaging, cancer ...
Ming-Fang Cheng   +5 more
doaj   +1 more source

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