Results 51 to 60 of about 34,030 (309)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Currency Options in Function of Currency Risk Hedging and Speculating

open access: yesEconomic Analysis, 2017
Due to current monetary policy of National Bank of Serbia which is focused on targeting the inflation rate, and therefore the introduction of a flexible foreign exchange rate policy which includes foreign exchange rate fluctuations, there is need for ...
Miljana Barjaktarović   +2 more
doaj  

Export of agricultural products as a determinant of currency security of Ukrainian economy

open access: yesAgricultural and Resource Economics
Purpose. The purpose of this study is the development of the methodological approach for estimation the impact of agri-food exports on the monetary sphere of Ukraine in order to substantiate the prospective directions of the export potential of ...
Victoria Kovalenko   +4 more
doaj   +1 more source

Market Efficiency of Euro Exchange Rates and Trading Strategies

open access: yesNaše Gospodarstvo, 2021
This paper tests the hypothesis on market efficiency for returns on the euro against fifteen currencies while assuming predictability of returns, dependent on the sign and magnitude of endogenous shocks.
Bošnjak Mile   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Fixing Exchange Rate of Currency Units Within the Frames of the Effective Monetary System

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2019
In current conditions of unstable global currency system and spoilt reputation of the American dollar the possibility to pass over to national currency in settlements among countries has become very topical.
Yu. A. Kropin
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Assessment of Key factors of the foreign Exchange Rate formation in armenia

open access: yesФинансы: теория и практика, 2018
Usually, it is diffcult for developing countries to choose a currency regulation policy because of institutional inadequacy, including a signifcant level of concentration in commodity markets, and a high degree of dependence of the national market and ...
E.  M. Sandoyan   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

European monetary union: limits to growth or bifurcation point [PDF]

open access: yesInternational Economic Policy, 2014
The paper presents the background and process of the EU monetary union establishment with regard to historical experience of European countries involving previous attempts of currency integration between separate countries.
Oleksandr Sharov
doaj  

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