Results 51 to 60 of about 526,911 (292)
Il mercato delle eurovalute come "sostituto" di altre fonti di credito
Moneta e Credito, 2014 The inflationary implications of the Euro-currency market continue to be a source of contention and misunderstanding. One view on the matter is that the market, having some potential for net credit creation, adds dangerously to the rate of world credit ...
W.D. MCCLAM
doaj +1 more source
Import Substitution: the Boarders of the Energy Security
Vestnik MGIMO-Universiteta, 2016 The article analyzes issues of import substitution in national production and determination of its effective scale considering the country's involvement to international division of labor and an important role of interstate cooperation in today's ...
Nikolay N. Shvets
doaj +5 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The substitution account: the problem, the techniques and the politics
PSL Quarterly Review, 2013 The present paper argues that in a longer-term perspective many of the problems and difficulties which caused the Substitution Account (SA) project to be scrapped are not as compelling as they previously appeared to be.
S. MICOSSI, F. SACCOMANNI
doaj +1 more source
Ratchet Effects in Currency Substitution An Application to the Kyrgyz Republic [PDF]
SSRN Electronic Journal, 1999 Currency substitution is now a common issue in the design of monetary policy in most transition economies. This paper analyzes the persistence of this phenomenon in the Kyrgyz Republic by including a ratchet variable in the model specification. The main conclusion of the paper is that, while some degree of persistence is present in the allocation of ...
Joannes Mongardini, Johannes Mueller
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
South African Journal of Economic and Management Sciences, 2004 The study set out to test the McKinnon-Shaw proposition that financial liberalization will significantly increase savings mobilization. The results partly supported the financial liberalization proposition.
M Aziakpono, S B-Obasa
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source