Results 81 to 90 of about 10,252,256 (302)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Programmable Current-Mode Universal Active Filters Employing Current Conveyors

open access: yesActive and Passive Electronic Components, 1998
Novel current-mode active filter circuits using current-conveyors are presented. The proposed circuits can realize all standard second-order filter functions.
Muhammad Taher Abuelma'atti
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Bayesian Mode Regression [PDF]

open access: yes, 2014
This article has been made available through the Brunel Open Access Publishing Fund.Like mean, quantile and variance, mode is also an important measure of central tendency of a distribution.
Yu, K, Aristodemou, K, Lu, Z
core   +1 more source

New Current-Mode Oscillators Using Unity-Gain Current-Followers

open access: yesActive and Passive Electronic Components, 1995
A catalog of current-mode oscillator circuits using negative unity-gain current-followers is presented. Each circuit uses two unity-gain current-followers, three resistors, and three capacitors .
Muhammad Taher Abuelma'atti
doaj   +1 more source

CMCS: Current-Mode Clock Synthesis

open access: yesIEEE Transactions on Very Large Scale Integration (VLSI) Systems, 2017
In a high-performance VLSI design, the clock network consumes a significant amount of power. While most existing methodologies use voltage-mode (VM) signaling, these clock distributions lose a tremendous amount of dynamic power to charge/discharge the large global clock capacitance. New circuit approaches for current-mode (CM) clocking save significant
Riadul Islam, Matthew R. Guthaus
openaire   +5 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Current-induced modification of spin wave mode interference

open access: yes, 2018
We have studied the effect of adiabatic spin-transfer torque on mode interference of spin waves. The mode interference generates amplitude-localized spots at special positions which do not move with time.
Lee, SW, Lee, HW, Lee, KJ
core   +1 more source

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