Results 181 to 190 of about 6,601,510 (205)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Current practices, opportunities to improve, and behavioral targets related to HPV vaccination in community pharmacies: A qualitative study of pharmacy staff and parents. [PDF]

Hum Vaccin Immunother
Schwartz J, Meehan K, Cohn EB, Bacci JL, Calo WA, Ko LK, Shah PD.   +6 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Discordance in the 2018 Periodontal Classification: Conceptual Challenges and a Biologically Grounded Framework for Interpretation. [PDF]

Dent J (Basel)
Hashim NT, Gismalla BG, Kukreja BJ, Ahmed A, Chaitanya NCSK, Abduljalil SMA, Elsidig HA, Rahman MM.   +7 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Impedance changes in chronic vagus nerve stimulator implantation in epileptic dogs. [PDF]

Vet Res Commun
Harcourt-Brown TR.
europepmc   +1 more source

Talkative battery: super-safe batteries with power-modulation based internal and external sensor data collection. [PDF]

Commun Eng
Diers J, Beiranvand H.
europepmc   +1 more source

Thermal Utilization on Chip. [PDF]

Light Sci Appl
Zhang Y, Lai B, Yu F, Li X, Yang Y, Lü W, Jiang K, Sun X, Li D.   +8 more
europepmc   +1 more source

Suppressing dendrites <i>via</i> lateral lithium flux in Li metal solid-state batteries.

Energy Environ Sci
Zhang H, Okur F, Klimpel M, Baumgärtner JF, Šivavec J, Müller A, Neporozhnii I, Kibrisli O, Voznyy O, Romanyuk YE, Kovalenko MV, Kravchyk KV.   +11 more
europepmc   +1 more source