Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Combined Nav1.7-Nav1.8 channel abrogation: Supralinear suppression of excitability in a subpopulation of peripheral sensory neurons. [PDF]
Vasylyev D +4 more
europepmc +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Assessment of sex inequalities in current tobacco smoking across 165 countries: a WHO Health Equity Assessment Toolkit analysis. [PDF]
Alhassan A +5 more
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Physiological 17β-oestradiol inhibits K<sub>V</sub>7.4 currents via GPER1-dependent PLC/PKC signalling. [PDF]
Karabatak E +5 more
europepmc +1 more source
ARTGEL: A temperature-regulated gel electrophoresis platform for quantitative studies of reversible association. [PDF]
Saha R, Fraden S.
europepmc +1 more source
Association of Adhesive Small Bowel Obstruction with Postoperative Health-related Quality of Life after Colorectal Cancer Surgery. [PDF]
Fu J +11 more
europepmc +1 more source
A Unified Model for Voltage-Source and Current-Source Virtual Synchronous Generators. [PDF]
Wang D +5 more
europepmc +1 more source

