Results 171 to 180 of about 4,453,263 (297)

Current state of glycemic control in critically ill subjects in a general intensive care unit

open access: yes, 2012
Vasileios Zochios1, Jonathan Wilkinson2, Jonathan Perry11University Hospitals of Leicester NHS Trust, Leicester, UK; 2Northampton General Hospital NHS Trust, Northampton, UKAbstract: Critically ill patients are predisposed to stress-induced hyperglycemia.
Wilkinson J, Perry J, Zochios V
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Design and Simulation of TCSC Control Model Based on Inductor Current

open access: yes, 2016
Flexible AC Transmission Systems (FACTS) is a novel transmission technology which is being recently developed at home and abroad. FACTS actualize the flexible control of AC Transmission Systems through adopting the newest achievement of electron ...
Du JS(杜劲松), Su R(苏锐)
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Verification of Current Sensorless Control for Single-Phase NPC Multilevel Inverter

open access: yes
The current control is becoming a challenging task for switched mode power supplies, while current sensorless control solutions can avoid the instantaneous current measurements that has been applied for mostly used power factor correction topologies ...
Zaķis, Jānis   +3 more
core  

United States Current Account Deficits: A Stochastic Optimal Control Analysis [PDF]

open access: yes
The "Pessimists" and the "Optimists" disagree whether the US external deficits and the associated buildup of US net foreign liabilities are problems that require urgent attention. A warning signal should be that the debt ratio deviates significantly from
Jerome L. Stein
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy