Results 71 to 80 of about 157,722 (307)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Modeling and Analysis of a PCM-Controlled Boost Converter Designed to Operate in DCM

Energies, 2018
Peak current-mode (PCM) control has been a very popular control method in power electronic converters. The small-signal modeling of the dynamics associated with PCM control has turned out to be extremely challenging.
Teuvo Suntio
doaj   +1 more source

Voltage regulation considerations for the design of hybrid distribution transformers [PDF]

, 2014
The future substation depends on finding a way to mitigate the effects of the drawbacks of the conventional legacy by employing the efficiency of the solid state switches [1].
Alqarni, M, Darwish, M, Radi, MA
core   +1 more source

Dynamics of current controlled quadratic boost converters

Acta Physica Sinica, 2013
The two inductor current boundaries are derived, and segmented smooth iteration mapping model of current controlled quadratic boost converter is established based on the detailed description of switching states. The comparative analyses of the nonlinear bifurcation behaviors are performed with input inductor current and the storage inductor current as ...
null Yang Ping, null Xu Jian-Ping, null He Sheng-Zhong, null Bao Bo-Cheng   +3 more
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Boost PFC converter based on feedforward harmonic decoupling control

Diance yu yibiao
The high penetration trend of power electronic equipment in local distribution network has led to the concentration, decentralization and wide area of harmonic sources, and the traditional point-to-point harmonic suppression is no longer applicable ...
ZHANG Rongfei, LIU Xueshan, WANG Chuntao, ZHOU Qun   +3 more
doaj   +1 more source

Stabilizing control for power converters connected to transmission lines [PDF]

, 2007
This paper proposes a switching control strategy for the set-point stabilization of a power converter connected via a transmission line to a resistive load.
Buisson, Jean,, Schaft, Arjan van der,, Zainea, Marius,   +2 more
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Converter design techniques and applications [PDF]

Transistorized direct current voltage converters offer a number of advantages over other types because of their small size, low weight, high efficiency, high reliability, precision accuracy and wide range of control.
Lalli, V. R.
core   +1 more source