Results 81 to 90 of about 11,879,309 (302)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Ocular toxoplasmosis in immunocompetent adults: current cost-effectiveness of four treatment regimens in Colombia. [PDF]

open access: yesHeliyon, 2021
Álvarez-García V   +4 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Min-Max Predictive Control of a Five-Phase Induction Machine

open access: yesEnergies, 2019
In this paper, a fuzzy-logic based operator is used instead of a traditional cost function for the predictive stator current control of a five-phase induction machine (IM).
Daniel R. Ramirez   +3 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Finite Control Set Model Predictive Current ControlFCS-MPC Based on Cost Function Optimization,with Current Limit Constraints for Four-Leg VSI [PDF]

open access: yesIraqi Journal for Electrical and Electronic Engineering, 2016
A Matlab/Simulink model for the Finite Control Set Model Predictive current Control FCS-MPC based on cost function optimization, with current limit constraints for four-leg VSI is presented in this paper, as a new control algorithm. The algorithm selects
Riyadh G. Omar, Rabee' H. Thejel
doaj  

Cost-effective sensor for residual current detection in residential DC microgrids [PDF]

open access: yesProceedings of the Estonian Academy of Sciences
Several developments in the fields of power electronics and materials science have turned direct current (DC) power grids, which have remained in the background until now, into attractive alternatives to the existing alternating current (AC)-based power ...
Tanel Jalakas   +2 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Current cost accounting: its role in regulated utilities [PDF]

open access: yes
Current cost accounting (CCA) was an important issue in financial accounting in the 1980s. In the UK, an accounting standard (SSAP 16, 1980) required supplementary CCA disclosures by large companies, but widespread noncompliance led to its being made non-
Geoffrey Whittington
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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