Results 121 to 130 of about 8,247,821 (276)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Features of designing internal power supply circuits for micropower ICs based on injection logic elements

Технологія та конструювання в електронній апаратурі, 2008
Control of the ohmic resistance of “hidden layers” of the n+-type using a mathematical model based on an elementary cell of equivalent lumped conductance with partitioning along two coordinates makes it possible to significantly reduce the variation of ...
A. I. Belous, V. A. Emel’yanov, V. S. Syakersky, A. V. Silin   +3 more
doaj  

Current distribution monitoring enables quench and damage detection in superconducting fusion magnets. [PDF]

Sci Rep, 2022
Teyber R, Weiss J, Marchevsky M, Prestemon S, van der Laan D.   +4 more
europepmc   +1 more source

PRODUCER BARGAINING: ITS CURRENT STATUS AND DISTRIBUTION OF BENEFITS [PDF]

Industrial Organization,
Berry, Calvin R.
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

The current distribution of tick species in Inner Mongolia and inferring potential suitability areas for dominant tick species based on the MaxEnt model. [PDF]

Parasit Vectors, 2023
Ma R, Li C, Tian H, Zhang Y, Feng X, Li J, Hu W.   +6 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Magnetic Sensor Array for Electric Arc Reconstruction in Circuit Breakers

Sensors
Noninvasive imaging of circuit breakers under short-circuit testing is addressed by recording the magnetic field produced over an array of external sensors and by solving an inverse problem to identify the causing current distribution.
Gabriele D’Antona, Luca Ghezzi, Sara Prando, Francesco Rigamonti   +3 more
doaj   +1 more source

Current distribution of distributed all-polar cochlear implant stimulation mode measured in-situ. [PDF]

PLoS One, 2022
Stahl P, Dang K, Vandersteen C, Guevara N, Clerc M, Gnansia D.   +5 more
europepmc   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source