Results 111 to 120 of about 4,605,835 (303)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Study on the process of preparing Al-Ce alloy by electrodeposition

Metalurgija, 2019
The process of Al-Ce alloy prepared by electrodeposition was studied in molten LiF-KCl-CeF3 salt at 820 °C. Several process parameters such as back electromotive force and current efficiency were measured by continuous pulse oscillograph.
J. D. Li, H. Ren, Z. Gong, K. Wang, Y. Y. Wang, J. L. Lu, J. Li   +6 more
doaj  

Effect of losses in an active device and harmonic network on the efficiency of Class F and inverse Class F power amplifiers [PDF]

, 2012
High frequency class F and inverse class F power amplifiers obtain high efficiency of dc to ac power conversion, by reducing the overlap of voltage and current waveforms at the output of the active device, to ensure that the power dissipated in the ...
Danaher, Sean, Ghassemlooy, Zabih, Korolkiewicz, Edward, Liu, Lei, Lu, Qing, Sambell, Alistair   +5 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Implications of WMAP Observations On the Population III Star Formation Processes

, 2003
In an earlier paper (Cen 2003) we pointed out the strong likelihood for the universal reionization to occur twice, giving rise to a larger Thomson optical depth.
Glatzel W., Renyue Cen
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Electrochemical Synthesis of Ferrate (VI) by Regular Anodic Replacement

International Journal of Electrochemical Science, 2015
Ferrate (VI) is a green water treatment agent which possesses the function of oxidation, disinfection and coagulation. Electrochemical generation of ferrate (VI) by replacing anode regularly was studied in different models of a two-compartment batch ...
Hongyu Wang, Yibing Liu, Fancheng Zeng, Shuang Song   +3 more
doaj   +1 more source

On Complexity, Energy- and Implementation-Efficiency of Channel Decoders

, 2010
Future wireless communication systems require efficient and flexible baseband receivers. Meaningful efficiency metrics are key for design space exploration to quantify the algorithmic and the implementation complexity of a receiver.
Kienle, Frank, Meyr, Heinrich, Wehn, Norbert   +2 more
core   +1 more source