Results 71 to 80 of about 2,070,503 (296)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Regularity for Micropolar Fluid Equations Subjected to Hall Current

open access: yesJournal of Applied Mathematics
In this paper, we consider the density-dependent incompressible Hall-magnetomicropolar fluid equations and establish a regularity condition involving the Lt1Lx∞ norm of the velocity gradient and the microrotational velocity gradient and the Lt2r/r−3Lxr ...
Mingyu Zhang
doaj   +1 more source

Fluid management in major burn injuries

open access: yesIndian Journal of Plastic Surgery, 2010
It is a widely accepted fact that severe fluid loss is the greatest problem faced following major burn injuries. Therefore, effective fluid resuscitation is one of the cornerstones of modern burn treatment.
Haberal Mehmet   +2 more
doaj   +3 more sources

Noncommutative fluid dynamics in the K\"{a}hler parametrization

open access: yes, 2011
In this paper, we propose a first order action functional for a large class of systems that generalize the relativistic perfect fluids in the K\"{a}hler parametrization to noncommutative spacetimes.
A. Connes   +6 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Current research in cavitating fluid films [PDF]

open access: yes
A review of the current research of cavitation in fluid films is presented. Phenomena and experimental observations include gaseous cavitation, vapor cavitation, and gas entrainment. Cavitation in flooded, starved, and dynamically loaded journal bearings,
Ball, J. H.   +2 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Gravity/Fluid Correspondence and Its Application on Bulk Gravity with U(1) Gauge Field

open access: yesAdvances in High Energy Physics, 2014
As the long wavelength limit of the AdS/CFT correspondence, the gravity/fluid correspondence has been shown to be a useful tool for extracting properties of the fluid on the boundary dual to the gravity in the bulk. In this paper, after briefly reviewing
Ya-Peng Hu, Jian-Hui Zhang
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Microscopic Current Dynamics in Nanoscale Junctions

open access: yes, 2007
So far transport properties of nanoscale contacts have been mostly studied within the static scattering approach. The electron dynamics and the transient behavior of current flow, however, remain poorly understood.
G. F. Giuliani   +12 more
core   +1 more source

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