Results 81 to 90 of about 13,927,530 (310)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Stochastic Variational Formulations of Fluid Wave–Current Interaction [PDF]

Journal of Nonlinear Science, 2020
AbstractWe are modelling multiscale, multi-physics uncertainty in wave–current interaction (WCI). To model uncertainty in WCI, we introduce stochasticity into the wave dynamics of two classic models of WCI, namely the generalised Lagrangian mean (GLM) model and the Craik–Leibovich (CL) model.
openaire   +3 more sources

Fluid Therapy in Acute Pancreatitis—Current Knowledge and Future Perspectives

Pharmaceuticals
Acute pancreatitis (AP) is one of the most frequent diseases requiring hospitalization in gastroenterology or intensive care unit departments. Its incidence and hospitalization rates have steadily increased over the last few years, contributing to high ...
Miłosz Caban, Hubert Zatorski, Ewa Małecka-Wojciesko   +2 more
doaj   +1 more source

Biomarkers for Alzheimer's disease: current status and prospects for the future

Journal of Internal Medicine, 2018
Accumulating data from the clinical research support that the core Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarkers amyloid‐β (Aβ42), total tau (T‐tau), and phosphorylated tau (P‐tau) reflect key elements of AD pathophysiology.
K. Blennow, H. Zetterberg
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gravity/Fluid Correspondence and Its Application on Bulk Gravity with U(1) Gauge Field

Advances in High Energy Physics, 2014
As the long wavelength limit of the AdS/CFT correspondence, the gravity/fluid correspondence has been shown to be a useful tool for extracting properties of the fluid on the boundary dual to the gravity in the bulk. In this paper, after briefly reviewing
Ya-Peng Hu, Jian-Hui Zhang
doaj   +1 more source

RETOUCH: The Retinal OCT Fluid Detection and Segmentation Benchmark and Challenge

IEEE Transactions on Medical Imaging, 2019
Retinal swelling due to the accumulation of fluid is associated with the most vision-threatening retinal diseases. Optical coherence tomography (OCT) is the current standard of care in assessing the presence and quantity of retinal fluid and image-guided
Hrvoje Bogunović, F. Venhuizen, S. Klimscha, Stefanos Apostolopoulos, A. Bab-Hadiashar, Ulas Bagci, M. Beg, Loza Bekalo, Qiang Chen, Carlos Ciller, Karthik Gopinath, A. Gostar, Kiwan Jeon, Zexuan Ji, S. Kang, D. Koozekanani, Donghuan Lu, Dustin Morley, Keshab K. Parhi, Hyoung Suk Park, A. Rashno, M. Sarunic, S. Shaikh, J. Sivaswamy, Ruwan Tennakoon, Shivin Yadav, Sandro De Zanet, S. Waldstein, B. Gerendas, C. Klaver, C. I. Sánchez, U. Schmidt-Erfurth   +31 more
semanticscholar   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source