Results 71 to 80 of about 2,146,824 (297)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 1973 An electromechanical actuator for producing mechanical force and/or motion in response to electrical signals is disclosed. The actuator includes a ferromagnetic fluid and a coil which are contained within an elastomeric capsule.
Sabelman, E. E.
core +1 more source
Regularity for Micropolar Fluid Equations Subjected to Hall Current
Journal of Applied MathematicsIn this paper, we consider the density-dependent incompressible Hall-magnetomicropolar fluid equations and establish a regularity condition involving the Lt1Lx∞ norm of the velocity gradient and the microrotational velocity gradient and the Lt2r/r−3Lxr ...
Mingyu Zhang
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
The pH and ionic composition of the sub-embryonic fluid of the Japanese quail (Coturnix c. japonica) [PDF]
, 2005 The current theory of acid-base chemistry regards [H+] as a dependent variable: changes in pH of a fluid can only occur by alteration of strong ion concentrations ([Na+], [K+], [Cl-]).
Baggott, Glenn K., Pellet-Many, C
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Current research in cavitating fluid films [PDF]
A review of the current research of cavitation in fluid films is presented. Phenomena and experimental observations include gaseous cavitation, vapor cavitation, and gas entrainment. Cavitation in flooded, starved, and dynamically loaded journal bearings,
Ball, J. H. +2 more
core +1 more source
Relativistic Viscous Fluid Dynamics and Non-Equilibrium Entropy
, 2010 Fluid dynamics corresponds to the dynamics of a substance in the long wavelength limit. Writing down all terms in a gradient (long wavelength) expansion up to second order for a relativistic system at vanishing charge density, one obtains the most ...
Andersson N +18 more
core +1 more source