Results 121 to 130 of about 19,714,201 (367)

Tunneling Current Measurement Scheme to Detect Majorana Zero Mode Induced Crossed Andreev Reflection [PDF]

, 2017
Lei Fang, D. Schmeltzer, Jian‐Xin Zhu, Avadh Saxena   +3 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Rogowski Coil for Current Measurement in a Cryogenic Environment

Measurement Science Review, 2015
A Rogowski coil based sensor for current measurement in a cryogenic environment and results of its application for paralleled high temperature superconducting (HTS) coil current sharing are presented. The current sensor consists of a Rogowski coil and an
Ma Tao, Dai Shaotao, Zhang Jingye, Zhao Lianqi   +3 more
doaj   +1 more source

Study on Spatial-Temporal Distribution Characteristics of the Discharge Process in a 1 m Rod-Plate Gap Under Different Polarity Lightning Impulses

IEEE Access, 2019
The observation of the air gap discharge process is the basis of revealing the physical mechanism of gas discharge and establishing the accurate numerical simulation model.
Yaqi Zhang, Yongxia Han, Wenbo Zheng, Jie Yang, Lu Qu, Gang Liu, Xiangen Zhao, Licheng Li   +7 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Measurement realities of current collection in dynamic space plasma environments [PDF]

Theories which describe currents collected by conducting and non-conducting bodies immersed in plasmas have many of their concepts based upon the fundamentals of sheath-potential distributions and charged-particle behavior in superimposed electric and ...
Szuszczewicz, Edward P.
core   +1 more source

Vancomycin and Aminoglycoside Antibiotic Drug Concentration Measurement: Current Status in Clinical Laboratories in Korea

, 2020
Won Kyung Kwon, Jongwon Oh, Soo‐Youn Lee, Hyung‐Doo Park   +3 more
openalex   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Non-invasive measurement of currents in analog quantum simulators [PDF]

, 2021
Kevin T. Geier, Janika Reichstetter, Philipp Hauke   +2 more
openalex   +1 more source