Results 131 to 140 of about 1,755,289 (266)

Heart Rate Variability and Direct Current Measurement Characteristics in Professional Mixed Martial Arts Athletes. [PDF]

Sports (Basel), 2020
Coyne JOC, Coutts AJ, Fomin R, French DN, Newton RU, Haff GG.   +5 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Pilot Evaluation of Intestinal Current Measurement in Cystic Fibrosis and CRMS/CFSPID Patients in Poland. [PDF]

J Clin Med
Postek M, Zybert K, Wozniacki L, Woynarowski M, Sands D.   +4 more
europepmc   +1 more source

Intestinal current measurement and nasal potential difference to make a diagnosis of cases with inconclusive CFTR genetics and sweat test. [PDF]

BMJ Open Respir Res, 2020
Minso R, Schulz A, Dopfer C, Alfeis N, Barneveld AV, Makartian-Gyulumyan L, Hansen G, Junge S, Müller C, Ringshausen FCC, Sauer-Heilborn A, Stanke F, Stolpe C, Tamm S, Welte T, Dittrich AM, Tümmler B.   +16 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Autonomous Lightning Strike Detection and Counting System Using Rogowski Coil Current Measurement. [PDF]

Sensors (Basel)
Andrade AF, Galdino GMB, Souza RT, Fonseca NSSM, Leite Neto AF, Costa EG, Carvalho Junior EL.   +6 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Intestinal current measurement detects age-dependent differences in CFTR function in rectal epithelium. [PDF]

Front Pharmacol
Graeber SY, Sommerburg O, Yu Y, Berges J, Hirtz S, Scheuermann H, Berger J, Duerr J, Mall MA.   +8 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Toward in vivo bronchoscopic functional CFTR assessment using a short circuit current measurement probe. [PDF]

Am J Physiol Lung Cell Mol Physiol
Otuya DO, Liu Z, Joseph R, Hanafy MA, Vijaykumar K, Stanford D, Raju SV, Baker EH, Rowe SM, Tearney GJ, Solomon GM.   +10 more
europepmc   +1 more source