Results 71 to 80 of about 2,304,730 (298)

Comparison of Current Ratio Errors of Support and Toroidal Type CTs in Electric Power Systems: A Case Study

open access: yesIEEE Access
A current transformer (CT) is a specialized device used to reduce high current values to safe and manageable levels in measurement and protection systems. Current ratio error (CRE) is an inevitable error in CTs due to factors such as magnetic saturation,
Ishak Ozer, Ali Unluturk
doaj   +1 more source

Precise comparison of theory and new experiment for the Casimir force leads to stronger constraints on thermal quantum effects and long-range interactions

open access: yes, 2005
We report an improved dynamic determination of the Casimir pressure between two plane plates obtained using a micromachined torsional oscillator. The main improvements in the current experiment are a significant suppression of the surface roughness of ...
Decca, R. S.   +5 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Error Data Analytics on RSS Range-Based Localization

open access: yesBig Data Mining and Analytics, 2020
The quality of measurement data is critical to the accuracy of both outdoor and indoor localization methods. Due to the inevitable measurement error, the analytics on the error data is critical to evaluate localization methods and to find the effective ...
Shuhui Yang, Zimu Yuan, Wei Li
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Performance analysis of Electromechanical and Smart meters under current and voltage harmonics

open access: yesInternational Journal of Electrical Engineering and Applied Sciences, 2020
One of the important characteristics of energy meters is their accuracy. Due to the continuous increase of energy and especially electricity tariffs, consumers are looking for accurate meters that give the right measurement. However, the use of nonlinear
Imene khenissi
doaj  

Decoherence in a Josephson junction qubit

open access: yes, 2003
The zero-voltage state of a Josephson junction biased with constant current consists of a set of metastable quantum energy levels. We probe the spacings of these levels by using microwave spectroscopy to enhance the escape rate to the voltage state.
A. Blais   +17 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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