Results 111 to 120 of about 8,916,715 (309)

International Risk Sharing and Investor Protection: Some Evidence from the EU-15 [PDF]

open access: yes
This note analyzes consumption risk sharing among the EU-15 countries. It is found that the reaction of consumption growth rates to idiosyncratic income growth is too sensitive to be consistent with perfect risk sharing.
Johann Scharler
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Optimized Design of Side-Connected Rectified Planar Transformer for Data Center DCX Modules

open access: yesEnergies
The rapid advancement of artificial intelligence (AI) has continuously boosted the computing power of data centers, imposing stringent requirements on the efficiency and power density of low-voltage high-current power modules.
Yang Cao   +4 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Resource Sharing News Issue (December 2009)

open access: yes, 2009
Table of Contents: Resource Sharing Update; New Web-based Interlibrary Loan Statistics; Aleph MNU & MII; Minitex Staff Attend Library Conferences in Three States; H1N1 and Staffing Issues; The Van; MnLINK VDX 4.1; Full Text Internet Newspaper Resources ...
Minitex Resource Sharing
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Topology Selection and Control Strategy for High-voltage Traction Battery Charger

open access: yes机车电传动, 2012
An input-series and output-paralleled (ISOP) circuit topology was very suitable for high input voltage to DC-DC conversion application. Relationship between the voltage sharing and the current sharing of ISOP topology was analyzed, which was concluded ...
谢伟   +4 more
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Design and Experimental Validation of a High-Current Marx Pulse Generator with Coordinated Voltage Balancing and Current Sharing Based on Series–Parallel IGBTs

open access: yesEnergies
Pulsed power systems require compact high-voltage pulse generators with high current capability, where series–parallel configurations of semiconductor switches are inevitable.
Cheng Yao   +5 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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