Results 71 to 80 of about 8,916,715 (309)

Car Sharing as a Key Contribution to Multimodal and Sustainable Mobility Behavior – the Situation of Car Sharing in Germany [PDF]

open access: yes, 2006
So far, car sharing is just a small niche product on the mobility market. The proven positive effects of car sharing can only contribute to solving traffic problems if the number of car sharing customers grows.
Nobis, Claudia
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

An Analytical Method to Optimize the Power Allocation of Parallel Converters for Maximizing Efficiency Across All Load Levels

open access: yesIEEE Access
For high-power conversion applications such as electric vehicle (EV) fast-chargers and wind power generation, multiple power electronic converters are often connected in parallel to reach high power levels with a modular design.
Mohammadhesam Hassani Sadi   +1 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Kon-tiki venture [cartographic material] /

open access: yes, 1950
Map of the Pacific Ocean showing route of Kon-tiki, Kuro Siwo and North Pacific drift, North and South Equatorial currents, Mexico current, Belt of Counter current, Peru or Humboldt's current, and South Pacific Connecting current.; "Map review no. 107, 3
Bureau of Current Affairs (London, England)
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Design of a Novel Active Gate Drive Circuit to Enhance Current Sharing in Parallel-Connected MOSFETs for Low-Voltage Inverter Applications

open access: yesIEEE Access
Low-voltage systems offer advantages in terms of safety, cost-effectiveness, and ease of integration, making them a preferred choice for e-scooters, light electric vehicles (LEVs), and various small-scale and urban mobility applications.
Berkay Keziban, Murat Yilmaz
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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