Results 131 to 140 of about 19,194,670 (349)

Stress and psychological wellbeing in local humanitarian workers in Colombia working for a local non-governmental organization : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University, Albany, New Zealand [PDF]

, 2008
This study examined the differences in stress and psychological wellbeing in 75 local humanitarian personnel (70 females and 5 males, median age = 30.7) from "Fundacion CC", local non-governmental organisation from Medellin, Colombia, who worked either ...
Abad, Jaime
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Comments on MHV Tree Amplitudes for Conformal Supergravitons from Topological B-Model

, 2005
We use the twistor-string theory on the B-model of CP^{3|4} to compute the maximally helicity violating(MHV) tree amplitudes for conformal supergravitons.
C.-J. Zhu, Changhyun Ahn, E. Ragoucy, E. Witten, F. Cachazo, F. Cachazo, G. Georgiou, G. Georgiou, J. Bedford, J.-B. Wu, J.-B. Wu, N. Berkovits, N. Berkovits, N.E.J. Bjerrum-Bohr, P.H. Ginsparg, R. Roiban, S. Giombi, S. Gukov, V.P. Nair, Z. Bern   +19 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Majorana Fermions Under Uniaxial Stress in Semiconductor-Superconductor Heterostructures

, 2013
Spin-orbit coupled semiconductor nanowires with Zeeman splitting in proximity contact with bulk $s$-wave superconductivity have recently been proposed as a promising platform for realizing Majorana fermions.
Chuanwei Zhang, Li Mao, Ming Gong, R. Winkler, Sumanta Tewari   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Survey of fracture toughness test methods [PDF]

, 1968
Comprehensive survey presents current methods of fracture toughness testing that are based on linear elastic fracture mechanics. General principles of the basic two dimensional crack stress field model are discussed in relation to real three dimensional ...
Brown, W. F., Jr., Jones, M. H., Srawley, J. E.   +2 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Oxidative Stress-Associated Male Infertility: Current Diagnostic and Therapeutic Approaches

Medicina
Infertility is a prevalent global issue affecting approximately 17.5% of adults, with sole male factor contributing to 20–30% of cases. Oxidative stress (OS) is a critical factor in male infertility, disrupting the balance between reactive oxygen species
Haritha Pavuluri, Zahra Bakhtiary, Manesh Kumar Panner Selvam, Wayne J. G. Hellstrom   +3 more
doaj   +1 more source