Results 41 to 50 of about 79,159 (315)
International Journal of Africa Nursing Sciences, 2023 Based on the authors’ experiences, this paper aims to describe and reflect on the project of developing and implementing simulation-based education in two nursing education programmes in Tanzania and Madagascar.The project lasted from August 2017 to ...
Ingrid Tjoflåt +3 more
doaj +1 more source
Discourse topic management and discussion skills in middle childhood: the effects of age and task [PDF]
, 2010 Discourse topic management and discussion skills are central for intersubjectivity, learning and education, yet there is little understanding of how such skills develop.The reported research comprises two studies, which examined the skills of discourse ...
Baines, Ed, Howe, Christine
core +2 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Curriculum: directions, decisions and debate [PDF]
, 2012 The purpose of this paper is to provide an overview of the factors which may effect, stimulate or be the cause of curriculum changes in higher education (HE) in Scotland. This overview leads to a series of questions which could be used to encourage debate within and across institutions on strategic developments, which may enhance and inform the ...
Fotheringham, Julia +2 more
openaire
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Curriculum Mapping for Curriculum Development: The Notion of “Curriculum Barcoding” in View of the Saudi Medical Education Directives Framework (SaudiMEDs) [PDF]
, 2022 Badr Alsayed, Ahmad A Omer
openalex +1 more source
Key Topics on End-of-Life Care for African Americans [PDF]
, 2006 Racial classifications of human populations are politically and socially determined. There is no biological or genetic basis for these racial classifications. Health behaviors may be influenced by culture and poverty.
Bernice Harper +23 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source