Results 111 to 120 of about 350,893 (316)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Damage identification in a concrete beam using curvature difference ratio
, 2011 Previous studies utilising changes in mode shape or curvature to locate damage rely on the fact that the greatest change occurs around the defect. However, in concrete beams this fact is undermined due to the nature of the defect as distributed multi ...
Mohammad, FA +7 more
core +1 more source
Evaluation and zoning of soil erosion potential using geomorphometric indexes and Fuzzy approach in Khiavchai watershed, Meshginshahr [PDF]
مطالعات جغرافیایی مناطق خشکAim: Erosion is a critical geomorphological process with significant environmental implications, including land degradation, fertility loss, and negative effects on aquatic ecosystems.
Faraiba Esfandyari Darabad +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Studies in History and Philosophy of Science, 2021 Dasgupta (2015) has recently put forward a novel argument, which he calls the 'curvature argument', that aims to show that Galilean spacetime is not an ideal setting for our classical theory of motion. This paper examines the curvature argument and argues that it is not sound.
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
An approximate solution for modes of curved optical fiber
Физика волновых процессов и радиотехнические системы, 2019 The paper presents an approximate analytical solution in closed form for the mode of a weakly guiding circular optical fiber with an arbitrary profile of the refractive index.
V.A. Burdin +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Curvature-specific color aftereffects
, 1975 Curvature-specific color ...
B Crassini (13634653), R Over (13279533)
core
Mean Curvature Dictates the Diffusion of Lipids Along Curved Membranes
, 2023 Curved cellular membranes are both abundant and functionally relevant. While novel tomography approaches reveal the structural details of curved membranes, their dynamics pose an experimental challenge.
Balázs, Fábián, Matti, Javanainen
core +1 more source