Results 41 to 50 of about 267,369 (299)

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Tax Curvature

SSRN Electronic Journal, 2021
In a Mirrleesian environment, a monopsonist sets hourly wages and individuals choose how many hours to work. Labor market outcomes do not only depend on the level and slope of the income tax function, but also on its curvature. A more concave tax schedule raises the elasticity of labor supply, which boosts wages.
openaire   +6 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Manipulation of anisotropic Zhang–Rice exciton in van der Waals antiferromagnets NiPS3-x Se x by anion substitution

npj 2D Materials and Applications
The spin-entangled Zhang-Rice (ZR) exciton observed in the van der Waals magnet NiPS3 has garnered significant interest due to its strong correlation with magnetic ordering and long coherence.
Deepu Kumar, Joydev Khatua, Nguyen The Hoang, Yumin Sim, Rajesh Kumar Ulaganathan, Raju Kalaivanan, Raman Sankar, Maeng-Je Seong, Kwang-Yong Choi   +8 more
doaj   +1 more source

Curvature and solidification [PDF]

Journal of Computational Physics, 1985
A method is presented for finding the osculating circle, and thus the curvature and the normal, of a curve defined by an array of partial volumes. This method is applied, within the framework of an enthalpy formulation, to the solutions of model equations that describe the motion of a front separating ice and supercooled water.
openaire   +2 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

On curvature and similarity.

Michigan Mathematical Journal, 1983
Let \(B_ 1(\Omega)\) denote the class of bounded Hilbert space operators T such that \(T-\lambda I\) is onto and has one dimensional kernel for \(\lambda \in \Omega\) and such that \(\bigvee_{\lambda \in \Omega}\ker(T- \lambda I)\) is dense in the Hilbert space.
Clark, Douglas N., Misra, Gadadhar
openaire   +2 more sources

On the scalar curvature and sectional curvatures of a Kaehler submanifold [PDF]

Proceedings of the American Mathematical Society, 1973
For a Kaehler submanifold of a complex space form, pinching for scalar curvature implies pinching for sectional curvatures. 1 . Statement of result. The scalar curvature is, by definition, the sum of Ricci curvatures with respect to an orthonormal basis of the tangent space, and the Ricci curvature is the sum of sectional curvatures.
Chen, Bang-Yen, Ogiue, Koichi
openaire   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source