Results 61 to 70 of about 217,455 (268)

Curves in the Lorentz-Minkowski plane with curvature depending on their position

open access: yesOpen Mathematics, 2020
Motivated by the classical Euler elastic curves, David A. Singer posed in 1999 the problem of determining a plane curve whose curvature is given in terms of its position. We propound the same question in the Lorentz-Minkowski plane, focusing on spacelike
Castro Ildefonso   +2 more
doaj   +1 more source

On curvature and similarity.

open access: yesMichigan Mathematical Journal, 1983
Let \(B_ 1(\Omega)\) denote the class of bounded Hilbert space operators T such that \(T-\lambda I\) is onto and has one dimensional kernel for \(\lambda \in \Omega\) and such that \(\bigvee_{\lambda \in \Omega}\ker(T- \lambda I)\) is dense in the Hilbert space.
Clark, Douglas N., Misra, Gadadhar
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

High-Myopia Diagnosis by Reciprocal of Circle Radius in Choroidal Image

open access: yesOptics
Light-emitting electronic devices are widely used at present, and this increases the risk of myopia. Thus, the early identification of myopia and the prevention of further exacerbation has become an essential issue in ophthalmology.
Shuo-Tsung Chen   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The Curve Shortening Flow in the Metric-Affine Plane

open access: yesMathematics, 2020
We investigated, for the first time, the curve shortening flow in the metric-affine plane and prove that under simple geometric condition (when the curvature of initial curve dominates the torsion term) it shrinks a closed convex curve to a “round point”
Vladimir Rovenski
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Thermal Transport in Nonlinear Unsteady Colloidal Model by Considering the Carbon Nanomaterials Length and Radius

open access: yesEnergies, 2020
Thermal transport analysis in colloidal suspension is significant from industrial, engineering, and technological points of view. It has numerous applications comprised in medical sciences, chemical and mechanical engineering, electronics, home ...
Syed Tauseef Mohyud-Din   +5 more
doaj   +1 more source

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