Results 81 to 90 of about 217,455 (268)

Sensory prediction on a whiskered robot: A tactile analogy to "optic flow"

open access: yesFrontiers in Neurorobotics, 2012
When an animal moves an array of sensors (e.g., the hand, the eye) through the environment, spatial and temporal gradients of sensory data are related by the velocity of the moving sensory array.
Christopher L Schroeder   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Evaluation and zoning of soil erosion potential using geomorphometric indexes and Fuzzy approach in Khiavchai watershed, Meshginshahr [PDF]

open access: yesمطالعات جغرافیایی مناطق خشک
Aim: Erosion is a critical geomorphological process with significant environmental implications, including land degradation, fertility loss, and negative effects on aquatic ecosystems.
Faraiba Esfandyari Darabad   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The curvature argument

open access: yesStudies in History and Philosophy of Science, 2021
Dasgupta (2015) has recently put forward a novel argument, which he calls the 'curvature argument', that aims to show that Galilean spacetime is not an ideal setting for our classical theory of motion. This paper examines the curvature argument and argues that it is not sound.
openaire   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

An approximate solution for modes of curved optical fiber

open access: yesФизика волновых процессов и радиотехнические системы, 2019
The paper presents an approximate analytical solution in closed form for the mode of a weakly guiding circular optical fiber with an arbitrary profile of the refractive index.
V.A. Burdin   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Curvature in plants

open access: yesCurrent Biology
Curvatures are ubiquitous in the animal kingdom - the spiral shell of the nautilus and the corkscrew horns of the blackbuck being iconic examples. Dynamic changes in curvature (i.e., curving) are most striking in the locomotion of some animal species - swimming in fishes and mollusks, looping in leeches, undulatory locomotion in snakes and lampreys ...
Hartmann, Félix   +2 more
openaire   +3 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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