Results 61 to 70 of about 725,568 (275)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
On area comparison and rigidity involving the scalar curvature [PDF]
In this thesis we study the effects of lower bounds for the curvature of a Riemannian manifold M on the geometry and topology of closed, minimal hypersurfaces.
Moraru, Vlad
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Wavefront division digital holography
AIP Advances, 2018 Digital holography (DH), mostly Mach-Zehnder configuration based, belongs to non-common path amplitude splitting interference imaging whose stability and fringe contrast are environmental sensitive.
Wenhui Zhang +6 more
doaj +1 more source
IEEE Photonics Journal, 2018 We proposed an optical fiber curvature sensor based on two microcollapses in silica capillary that was spliced between single-mode fibers. Only commercial fiber fusion splicer was needed in the fabrication process.
Ruikai Xue +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Path Planning and Analysis of Error Control in Abrasive Belt Grinding Free-form Surface
工程科学与技术, 2017 :Abrasive belt grinding is one of the important means to improve the accuracy and quality of free-form surface.Aiming at the shortcomings in the efficiency and accuracy in the process of belt grinding of free-form surface,based on the characteristics of ...
Huang Zhi +4 more
doaj
A model for the behavior of fluid droplets based on mean curvature flow [PDF]
, 2012 The authors of [W. D. Ristenpart et al., Nature, 461 (2009), pp. 377–380] have observed the following remarkable phenomenon during their experiments.
Helmensdorfer, Sebastian
core +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Jixie chuandong, 2015 The structure and transmission principle of the two tooth difference cycloid movable tooth transmission are introduced,and the tooth profile is designed. The tooth outline of center gear is analyzed with simulation software,and the radius of curvature of
Han Xiaojuan, Yang Maokun
doaj