Results 51 to 60 of about 725,568 (275)

Differential phase tracking applied to Bragg gratings in multicore fiber for high accuracy curvature measurement [PDF]

, 2006
We report interferometric interrogation of fiber Bragg gratings in separate cores of a multicore fiber for high resolution quasi-static and dynamic bend measurements.
Kirkendall, Clay K., Flockhart, Gordon M. H., Cranch, Geoffrey A.   +2 more
core   +2 more sources

Surface-Plasmon-Resonance-Based Optical Fiber Curvature Sensor with Temperature Compensation by Means of Dual Modulation Method

Sensors, 2018
Curvature measurement plays an important role in many fields. Aiming to overcome shortcomings of the existing optical fiber curvature sensors, such as complicated structure and difficulty in eliminating temperature noise, we proposed and demonstrated a ...
Yudong Su, Yong Wei, Yonghui Zhang, Chunlan Liu, Xiangfei Nie, Zongda Zhu, Lu Liu   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Numerical investigation on sealing performance of drainage pipeline inspection gauge crossing pipeline elbows

Energy Science & Engineering, 2021
A pipeline inspection gauge (PIG) is routinely passed throughout the long‐distance oil and gas pipelines by pipeline operators to clean the pipeline. Sealing performance is a significant evaluation index for PIG's safety operation.
Jinxu Jiang, Hong Zhang, Beilei Ji, Feining Yi, Feng Yan, Xiaoben Liu   +5 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Study on Meshing Characteristic of Face Gear Pair based on Pinion Modified by Continuous Shifting

Jixie chuandong, 2018
On the basis of processing principles of torus-involute gear,the longitudinal modification method based on continuous shifting is used for the pinion in the face gear drive,a modified face gear pair is obtained.
Zhang Jinzhao, Liu Lei
doaj  

A Multiscale Global Denoising Algorithm for Urban Airborne Array InSAR Point Clouds

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Array interferometric synthetic aperture radar (Array InSAR) enables high-precision three-dimensional point cloud reconstruction, but data quality is often degraded by environmental noise, channel amplitude–phase errors, and multipath interference.
Fangfang Ji, Jie Yu, Guoman Huang, Lijun Lu, Shucheng Yang, Wenxu Duan   +5 more
doaj   +1 more source

Meshing characteristics of a sphere–face gear pair with variable shaft angle

Advances in Mechanical Engineering, 2019
This article presents a sphere–face gear pair by substituting the convex spherical gear for the pinion of a conventional face gear pair. The sphere–face gear pair not only maintains the advantages of the face gear pair with a longitudinally modified ...
Lei Liu, Jinzhao Zhang
doaj   +1 more source