Results 151 to 160 of about 1,051,604 (281)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

A continuum membrane model can predict curvature sensing by helix insertion. [PDF]

Soft Matter, 2021
Fu Y, Zeno WF, Stachowiak JC, Johnson ME.   +3 more
europepmc   +1 more source

Stretchable Curvature Sensors for Motion Capture with Bending‐Stretching Coupling Deformation

Advanced Science
Accurate curvature sensing is essential for robotic control, movement monitoring, and enhanced interactive experiences. Existing strategies rely either on stretchable strain sensors, which introduce non‐calibratable measurement errors due to unstable ...
Tairan Wang, Xinkai Xu, Shuang Li, Yuqun Lan, Kai Chen, Wei Li, Guangyuan Wang, Kuai Yu, Lijuan Sun, Yewang Su   +9 more
doaj   +1 more source

Nanoplasmonic Sensing Architectures for Decoding Membrane Curvature-Dependent Biomacromolecular Interactions

, 2018
Nanoplasmonic sensors have emerged as a promising measurement approach to track biomacromolecular interactions involving lipid membrane interfaces. By taking advantage of nanoscale fabrication capabilities, it is possible to design sensing platforms with
Bita Malekian (4380721), Dahlin, Andreas, Soohyun Park, Malekian, Bita, Gustav Emilsson, Gustav Emilsson (1618420), Emilsson, Gustav, Park, Soohyun, Joshua A. Jackman (1488859), Andreas B. Dahlin, Kunli Xiong (1587484), Ferhan, Abdul Rahim, Joshua A. Jackman, Soohyun Park (5350040), Jackman, Joshua A., Cho, Nam Joon, Nam-Joon Cho (693259), Nam-Joon Cho, Jackman, J., Dahlin, Andreas B., Xiong, Kunli, Bita Malekian, Abdul Rahim Ferhan, Abdul Rahim Ferhan (1480126), Kunli Xiong, Andreas B. Dahlin (1587481), Cho, Nam-Joon   +26 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Insights into Membrane Curvature Sensing and Membrane Remodeling by Intrinsically Disordered Proteins and Protein Regions. [PDF]

J Membr Biol, 2022
Has C, Sivadas P, Das SL.
europepmc   +1 more source

Sensor fusion of touch & vision in soft manipulators for fruit picking

Nature Communications
Modern agricultural robotic systems are constrained by limited sensing and manipulation capabilities, particularly in fruit harvesting, where variability in color, size, and firmness poses significant challenges.
Anand Kumar Mishra, Aravind Ramaswami, Vikram Shree, Mehmet Mert Ilman, Khoi D. Ly, Marvin P. Pritts, Robert F. Shepherd   +6 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Correction: A continuum membrane model can predict curvature sensing by helix insertion. [PDF]

Soft Matter, 2022
Fu Y, Zeno WF, Stachowiak JC, Johnson ME.   +3 more
europepmc   +1 more source

In-Fiber Hybrid Structure Sensor Based on the Vernier Effect for Vector Curvature and Temperature Measurement

Photonics
A vector curvature and temperature sensor based on an in-fiber hybrid microstructure is proposed and experimentally demonstrated. The proposed scheme enables the dimensions of the Fabry–Perot and Mach–Zehnder hybrid interferometer to be adjusted for the ...
Sunde Wang, Tiantong Zhao, Baoqun Li, Silun Du, Deqi Li, Dongmei Liu, Tianshu Wang   +6 more
doaj   +1 more source