Results 71 to 80 of about 1,081,533 (280)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Reconciling modern machine learning practice and the bias-variance trade-off
, 2019 Breakthroughs in machine learning are rapidly changing science and society, yet our fundamental understanding of this technology has lagged far behind.
Belkin, Mikhail +3 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Pollination of a Canary Tree Flower
Undergraduate Journal of Mathematical Modeling: One + Two, 2010 Pollination is an essential part of the life cycle of flowering plants. We perform an experiment to determine how long a canary tree flower is accessible to pollinating insects so that fertilization can take place.
Abbie O'Hern Weeks
doaj +1 more source
Reconstruction of Velocity Distribution in Partially-Filled Pipe Based on Non-Uniform Under-Sampling
Advances in Mathematical Physics, 2020 In the process of research on the flow velocity distribution in a partially filled pipe, the under-sampling of measurement data often occurs. For the first time, this problem is solved by the improved non-uniform B-spline curve fitting approximation ...
Yulin Jiang, Qingmin Pu, Wenbin Ding
doaj +1 more source
A Critical Analysis of Dimensions and Curve Fitting Practice in Economics [PDF]
When dealing with sustainability we are concerned with the biophysical as well as the monetary aspects of economic and ecological interactions. This multidimensional approach requires that special attention is given to dimensional issues in relation to ...
Jesus Ramos-Martin +2 more
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Cooperative Optimization-Based Frequency-Domain Curve Fitting: Enhancing Accuracy and Efficiency
IEEE Open Journal of the Industrial Electronics SocietyThe frequency-domain curve fitting of dynamic system models in modal summation form is an essential process in mechatronics control, and it is widely used in various industries.
Shimpei Sato, Yoshihiro Maeda
doaj +1 more source