Results 91 to 100 of about 355,580 (298)
Wind Turbine Power Curves Based on the Weibull Cumulative Distribution Function
Applied Sciences, 2018 The representation of a wind turbine power curve by means of the cumulative distribution function of a Weibull distribution is investigated in this paper, after having observed the similarity between such a function and real WT power curves. The behavior
Neeraj Bokde +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 2011 Floods are complex and flood records tend to have errors. The two important points in flood frequency analysis are ‘1) All flood frequency curves are wrong, but some are useful; 2) ‘All data are wrong, but some are useful.’ The uncertainties with the ...
null Dawei Han
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Rational quadratic Bézier curve fitting by simulated annealing technique
, 2013 A metaheuristic algorithm, which is an approximation method called simulated annealing is implemented in order to have the best rational quadratic Bézier curve from a given data points.
Abd Rahni, Mt Piah +2 more
core
Reliability curve fitting for aging helicopter components
, 2016 This paper presents a comparison of alternative reliability curve fitting techniques for components of two model types of helicopters. Both mathematical function-based and neural network models were investigated.
James T. Luxhoj; Huan-Jyh Shyur
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Different curve fitting methods.
, 2014 ROC plots each for an individual reader using CT colonography without CAD. Green dots indicate real data points underlying curve fitting. ROC curve are shown extrapolated from these data using DBM MRMC (red dotted line) and PROPROC software (blue solid ...
Doug G. Altman (366200) +3 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source