Results 101 to 110 of about 355,580 (298)

Research on Vehicle Wheelset Wear Model Based on Measured Data

open access: yesChengshi guidao jiaotong yanjiu
Objective Based on the measured data of the train wheelsets on Shanghai Metro Line 17, the wheelset wear pattern is studied, and a wear model of wheel rim thickness and wheel diameter is established to improve the safety and maintenance efficiency of ...
DING Yaqi   +5 more
doaj   +1 more source

Curve-fitting and laboratory data

open access: yes, 1982
Evaluation of soil properties from laboratory tests requires the use of empirical procedures. It has proved difficult to establish procedures for identifying yield stresses that are independent of the stress path and the method of plotting ...
K. V. Lew   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A. The final WALA curve-fitting of Class II malocclusion:

open access: yes, 2014
a. WALA scatter diagrams of SC2 samples were processed by nonlinear regression analysis via SPSS 17.0. b. The fourth degree even order power function was utilized to analyze the curve fitting to represent the basal bone archform curves. c.
TianMin Xu (590053)   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Best curve-fitting test results.

open access: yes, 2013
Ranked list of the 12 best curve-fitting techniques studied for the synapse MCell Monte Carlo simulation data.
Elena Gomez (71616)   +4 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Benzene titration curve fitting.

open access: yes, 2018
Plot of the intensity decrease of 1-AMA fluorescence emission at 481 nm as a function of benzene concentration. In red color it is shown the fitting curve obtained by a non-linear function.
Antonio Varriale (297193)   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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