Results 41 to 50 of about 973 (234)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
, 2017 BS 243 higeomes Nr. 1100 Zone: DOst: 39.005727Nord: 36.570372 Lokalisierung: unsicher Toponyme: keine Angaben Erforschung: Survey Datierung: MBZ (1) Bibliographie: Curvers 1990 BS 244 higeomes Nr.
Fink, Christoph, Christoph Fink
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2017 Hajaje, Khirbat al- higeomes Nr. 700 Ḥaǧāǧa Zone: DOst: 39.097520Nord: 36.481697 Lokalisierung: unsicher Toponyme: keine Angaben Erforschung: Survey Datierung: SBZ (1) Bibliographie: Curvers 1990, Lyon 2000 BS 182 higeomes Nr.
Fink, Christoph, Christoph Fink
core +1 more source
Aa. Vv., «Bulletin des Amis d’André Gide», n. 155 [PDF]
, 2007 Dopo un articolo di Catherine Gravet, D’un portrait graphologique: «infiniment séduisant», in cui si disquisisce sulla “scienza” della grafologia ma ci si arricchisce anche di notizie su Gide, Hélène Legros, Aline Mayrisch e soprattutto sul protagonista,
Kanceff, Emanuele, Emanuele Kanceff
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source