Results 61 to 70 of about 973 (234)
Gravet (Catherine), dir., Cahiers internationaux de Symbolisme, numéro spécial 2008
, 2013 Singulier volume que ce numéro spécial des Cahiers internationaux de symbolisme, en fait recueil d’actes d’un colloque célébrant le cinquantième anniversaire du roman le plus réputé d’Alexis Curvers, Tempo di Roma.
Saint-Amand, Denis
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Le corps dans Phèdre de Sénèque et Hippolyte d'Euripide
, 2021 Nota : sauf précision contraire, toutes les traductions en français citées ici sont d’Olivier Sers (pour Sénèque) et de Marie Delcourt-Curvers (pour Euripide).
Jérôme
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2019 Auteurs grecs Les traductions d’Eschyle ou de Sophocle sont, sauf mention particulière, celles de Paul Mazon pour Les Belles Lettres. Pour Euripide, nous avons préféré la traduction de Marie Delcourt-Curvers, Euripide, Tragédies complètes, Paris ...
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Bernier (Yvon), Inventaire de la bibliothèque de Marguerite Yourcenar. Petite Plaisance
, 2013 De « Petite Plaisance », le 15 août 1955, Marguerite Yourcenar écrit à ses amis liégeois, Marie Delcourt et Alexis Curvers : « Chers Amis, Vos deux lettres sont sur ma table ; les livres sont sur les rayons de la bibliothèque [Marie Delcourt vient ...
Gravet, Catherine
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source