Results 51 to 60 of about 179 (157)

Mapping Causal Biology: Mendelian Randomization in the Era of Big Data

Med Research, EarlyView.
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen, Chunrun Qu, Zeyu Wang, Jinglin Zhou, Hongwei Liu, Yingjie Li, Bowei Liu, Hao Zhang, Nan Zhang, Jingwei Zhang, Quan Cheng   +10 more
wiley   +1 more source

New Dimension in Magnetism and Superconductivity: 3D and Curvilinear Nanoarchitectures. [PDF]

Adv Mater, 2022
Makarov D, Volkov OM, Kákay A, Pylypovskyi OV, Budinská B, Dobrovolskiy OV.   +5 more
europepmc   +1 more source

Ethnic integration and the value of innovation

Strategic Management Journal, EarlyView.
Abstract Research Summary Organizations have become increasingly ethnically diverse, and this diversity often brings together distinct technological competencies. Understanding how firms can leverage such diversity to produce valuable innovations therefore becomes essential.
Stefano Breschi, Luisa Gagliardi, Thomas Yoon   +2 more
wiley   +1 more source

Statistical Equilibrium Principles in 2D Fluid Flow: From Geophysical Fluids to the Solar Tachocline. [PDF]

Entropy (Basel), 2022
Weichman PB, Marston JB.
europepmc   +1 more source

Biomaterial‐Integrated Electroporation for Therapeutic Delivery: From Gene Editing to Tumor Ablation and Immune Modulation

Small, EarlyView.
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji, Zhuozhuo Wu, Yuyue Jiang, Xiaoyu Liu, Jingfeng Li, Fengkuo Xu, Chaojie Li, Qungang Shan, Ziyin Wang, Junhao Wang, Wei Huang, Yaping Zhuang, Wenguo Cui, Zhongmin Wang   +13 more
wiley   +1 more source

Mathematical Foundations of Adaptive Isogeometric Analysis. [PDF]

Arch Comput Methods Eng, 2022
Buffa A, Gantner G, Giannelli C, Praetorius D, Vázquez R.   +4 more
europepmc   +1 more source

Associations between transformational leadership, occupational stress and emotional exhaustion in UK veterinary professionals: A cross‐sectional study

Veterinary Record, EarlyView.
Abstract Background Occupational stress and burnout are prevalent concerns within the UK veterinary profession. Within the job demands–resources (JD‐R) framework, occupational stress represents a job demand linked to emotional exhaustion (EE), while transformational leadership (TL) may function as an organisational resource.
Roanneth Slater‐Brown
wiley   +1 more source

Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +2 more
wiley   +1 more source

Hyperactivation and Tyrosine Phosphorylation of Cryopreserved Stallion Spermatozoa in Relation to Conventional In Vitro Fertilization Blastocyst Production

Andrology, EarlyView.
ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro, Carolina C. Porflidt, Alexandra L. Ash, Jacobo S. Rodriguez, Perla D. Fleury, Edward L. Squires, Elaine M. Carnevale   +6 more
wiley   +1 more source

A balance between stability and flexibility: Adaptive patterns of self‐regulated learning processes shape game‐based learning

British Journal of Educational Technology, EarlyView.
Abstract To ensure learning efficiency in game‐based learning (GBL), learners must regulate cognitive, affective, metacognitive and motivational (CAMM) processes, collectively known as self‐regulated learning (SRL). SRL is dynamic and non‐linear, characterized by regulatory patterns and CAMM interactions that lead to macro‐level SRL behaviours. In this
Elizabeth B. Cloude, Stefan E. Huber, Jingwei Wei, Bianca Esmanhoto, Muhterem Dindar, Manuel Ninaus, Kristian Kiili   +6 more
wiley   +1 more source