Results 51 to 60 of about 11,283 (172)
The Bidirectional Association Between MASLD and Male Hypogonadism: An Updated Meta‐Analysis
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) and male hypogonadism are increasingly prevalent, metabolically interrelated conditions. Testosterone (T) deficiency has been implicated in hepatic lipid dysregulation, insulin resistance, and visceral adiposity, whereas MASLD may impair the hypothalamic–pituitary ...
Giorgia Spaggiari +9 more
wiley +1 more source
The treatment objectives for a patient with Cushing's disease (CD) are remission of hypercortisolism, adequate management of co-morbidities, restoration of the hypothalamic-pituitary-adrenal axis, preservation of fertility and pituitary function, and ...
Márcio Carlos Machado +13 more
doaj +1 more source
Hypogonadism in Cisgender Men Living With HIV: Prevalence, Clinical and Metabolic Features
ABSTRACT Background Hypogonadism is frequently observed in men living with human immunodeficiency virus (HIV), although its prevalence, etiology, and predictors remain incompletely understood. Objective To evaluate the prevalence of hypogonadism and its association with metabolic factors in men living with HIV (MLWH), on stable antiretroviral therapy ...
Felipe Augusto Azevedo Leao +8 more
wiley +1 more source
Genetics of Cushing's disease [PDF]
SummaryCushing's disease (CD) is a rare disabling condition caused by Adrenocorticotropic hormone (ACTH)‐secreting adenomas of the pituitary. The majority of corticotropic adenomas are monoclonal and occur sporadically. Only rarely does CD arise in the context of genetic familial syndromes.
Albani, Adriana +2 more
openaire +2 more sources
Pediatric Cushing's disease: Case reports and retrospective review
Background. We report four pediatric subjects with Cushing's disease (CD) diagnosed in the Czech Republic. We focus on initial symptoms of Cushing's syndrome (CS) which can lead to early diagnosis, on typical symptoms of CS in children, their age and sex
Renata Pomahacova +4 more
doaj +1 more source
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton +4 more
wiley +1 more source
Ectopic Cushing’s Syndrome: A Race Against Time
Cushing’s syndrome is characterized by a phenotype resulting from cortisol excess. To manage Cushing’s syndrome, the etiology must be defined. Cushing’s syndrome is broadly divided into adrenocorticotrophic hormone-dependent and adrenocorticotrophic ...
Pankaj Singhania +4 more
doaj
Abstract Objectives/Background Cluster headache (CH) has historically been considered a male‐dominated disorder, suggesting a role for androgens in its pathophysiology. We aimed to evaluate hormone profiles and symptoms of androgen deficiency in CH.
Willemijn C. Naber +7 more
wiley +1 more source
Advances in clinical diagnosis of Cushing's disease
Cushing's disease, also known as pituitary adrenocorticotrophin⁃secreting adenoma, is a rare and serious neuroendocrine disease. At present, the diagnosis of disease is mainly based on the patient's clinical manifestations, imaging examinations and ...
Bo⁃wen SUN +3 more
doaj
SEE YOUR ENDOCRINOLOGIST FOR A PITUITARY TUMOUR; YOU MAY NOT NEED SURGERY
Cushing’s syndrome remains an uncommon diagnosis with majority of non-specific and few specific clinical features suggestive of the condition. Results of biochemical investigations are often affected by confounding factors making diagnosis of Cushing’s ...
Ahmed Imran Siddiqi
doaj +1 more source

