Results 71 to 80 of about 11,283 (172)

Cushing’s disease – Same condition, different scenarios [PDF]

Archives of the Balkan Medical Union, 2018
Cushing’s disease is a rare pathology characterized by excess production of adrenocorticotropic hormone (ACTH) secondary to a pituitary adenoma which stimulates adrenal cortisol secretion.
Adina Ghemigian, Andra Cocolos, Paul Neagu, Nicoleta Dumitru, Simona E. Albu, Mara Carsote   +5 more
doaj  

Case of diabetic ketoacidosis as an initial presentation of Cushing’s syndrome

Endocrinology, Diabetes & Metabolism Case Reports, 2017
Diabetic ketoacidosis (DKA) is commonly encountered in clinical practice. The current case is a unique and rare presentation of DKA as the initial manifestation of Cushing’s disease secondary to ACTH-secreting pituitary adenoma. Appropriate management as
Runa Acharya, Udaya M Kabadi
doaj   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2719-2737, December 2026.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

A Giant 5000 g Primary Adrenocortical Carcinoma: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Adrenocortical carcinoma (ACC) is an aggressive malignancy that may present without hormonal symptoms. A 64 years old woman with abdominal pain, weight loss, and anemia had a massive adrenal tumor that required complex surgery. ACC should be considered in large abdominal masses. Complete surgical resection is essential.
Sadin Zahra, Aghajanzadeh Manouchehr, Mohammad Reza Sadin, Dadashi Arsalan, Poorsafar Mahdi, Aghzadeh Zeynab, Khyabani Mahmood, Shafaghi Afshin   +7 more
wiley   +1 more source

Glucocorticoid regulation of food-choice behavior in humans: Evidence from Cushing’s syndrome

Frontiers in Neuroscience, 2016
The mechanisms by which glucocorticoids regulate food intake and resulting body mass in humans are not well-understood. One potential mechanism could involve modulation of reward processing, but human stress models examining effects of glucocorticoids on
Scott J Moeller, Lizette eCuoto, Venessa eCohen, Yelena eLalazar, Iouri eMakotkine, Nia eWilliams, Rachel eYehuda, Rita Z Goldstein, Eliza B Geer   +8 more
doaj   +1 more source

Multiple Machine Learning Algorithms for Predicting Postoperative Residual Tumor in Pituitary Neuroendocrine Tumors

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
An explainable random forest–based machine learning model accurately predicted postoperative residual tumors in PitNETs, with tumor size and Knosp grade as major predictors, offering a web‐based tool for individualized surgical risk assessment and precision management.
Mingrui Li, Chenyang Zhao, Guodong Tang, Yang Li, Qing Liu   +4 more
wiley   +1 more source

Clinical outcomes of a novel flowable calcium silicate cement in equine endodontic treatment

Equine Veterinary Journal, Volume 58, Issue 6, Page 1602-1611, November 2026.
Abstract Background Orthograde endodontic treatment of equine cheek teeth is performed infrequently with variable success rates of obturation with calcium hydroxide paste (CHP). A novel flowable calcium silicate cement (eCSC) formulated for use as an obturation material in equine teeth has demonstrated acceptable canal filling volumes and evidence of ...
Kirsten Jackson, Josephine Faulkner, Carsten Staszyk, William Ha, Ebony Quintrell, Erin Kelty   +5 more
wiley   +1 more source

Cushing disease with pregnancy

Gynecological Endocrinology, 2012
Pregnancy occurs rarely in patients with Cushing syndrome (CS) due to hypercortisolism. So far, about 150 cases of CS in pregnancy have been reported in the literature. We describe a 22-year-old female who presented in pregnancy with clinical features of CS.
Raju A, Gopal, Shrikrishna V, Acharya, Tushar R, Bandgar, Padma S, Menon, Nalini S, Shah   +4 more
openaire   +2 more sources

Prevalência da hipertensão arterial na síndrome de Cushing.

Acta Médica Portuguesa, 1997
To determine the prevalence of hypertension (HT) in patients with Cushing's syndrome.We studied 23 patients with Cushing's syndrome, 17 women (mean +/- SD age = 42.8 +/- 15.6 years) and 6 men (mean +/- SD age = 34.8 +/- 10.2 years).
D Rodrigues, L Barros, L Ruas, L Gomes, E Geraldes, M C Ruas   +5 more
doaj   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, Volume 34, Issue 11, Page 2051-2060, November 2026.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source