Results 261 to 270 of about 23,806 (286)
Some of the next articles are maybe not open access.
Endocrinology and Metabolism Clinics of North America, 2008
Cushing's syndrome is a rare endocrine disease characterized by cortisol hypersecretion, induced mainly by a pituitary tumor (Cushing's disease) or, rarely, by an adrenal or an ectopic neuroendocine tumor. Cushing's syndrome is associated with severe morbidities and an increased mortality.
PIVONELLO, ROSARIO +4 more
openaire +6 more sources
Cushing's syndrome is a rare endocrine disease characterized by cortisol hypersecretion, induced mainly by a pituitary tumor (Cushing's disease) or, rarely, by an adrenal or an ectopic neuroendocine tumor. Cushing's syndrome is associated with severe morbidities and an increased mortality.
PIVONELLO, ROSARIO +4 more
openaire +6 more sources
The Lancet, 2023
Endogenous Cushing's syndrome results from excess glucocorticoid secretion, which leads to a myriad of clinical manifestations, comorbidities, and increased mortality despite treatment. Molecular mechanisms and genetic alterations associated with different causes of Cushing's syndrome have been described in the last decade.
Gadelha, Mônica +3 more
openaire +2 more sources
Endogenous Cushing's syndrome results from excess glucocorticoid secretion, which leads to a myriad of clinical manifestations, comorbidities, and increased mortality despite treatment. Molecular mechanisms and genetic alterations associated with different causes of Cushing's syndrome have been described in the last decade.
Gadelha, Mônica +3 more
openaire +2 more sources
Clinics in Endocrinology and Metabolism, 1985 Cushing's syndrome remains one of the most challenging problems in clinical endocrinology. Cushing's disease is caused in the majority of cases by basophil pituitary microadenomas which may be successfully treated by trans-sphenoidal hypophysectomy.
L.H. Rees, G.M. Besser, T.A. Howlett
openaire +2 more sources
Endocrinology and Metabolism Clinics of North America, 1989
The clinical characteristics and current concepts of pathophysiology of Cushing's syndrome have been reviewed. The specific type of pituitary or ectopic ACTH-dependent and ACTH-independent Cushing's syndrome and the underlying pathology can be determined biochemically and with the aid of anatomic localization procedures.
openaire +6 more sources
The clinical characteristics and current concepts of pathophysiology of Cushing's syndrome have been reviewed. The specific type of pituitary or ectopic ACTH-dependent and ACTH-independent Cushing's syndrome and the underlying pathology can be determined biochemically and with the aid of anatomic localization procedures.
openaire +6 more sources
The Indian Journal of Pediatrics, 2013
Cushing syndrome is the constellation of signs and symptoms caused by protracted exposure to glucocorticoids. The most common cause of Cushing syndrome in children and adolescents is exogenous administration of glucocorticoids. Presenting features commonly include weight gain, growth retardation, hirsutism, obesity, striae, acne and hypertension ...
Bibek Bista, Nancy Beck
openaire +3 more sources
Cushing syndrome is the constellation of signs and symptoms caused by protracted exposure to glucocorticoids. The most common cause of Cushing syndrome in children and adolescents is exogenous administration of glucocorticoids. Presenting features commonly include weight gain, growth retardation, hirsutism, obesity, striae, acne and hypertension ...
Bibek Bista, Nancy Beck
openaire +3 more sources
The Indian Journal of Pediatrics, 1997
Endogenous Cushing's Syndrome (CS) is a relatively uncommon disease in children. The etiology is more often a primary adrenal cause in infants and younger children, and corticotroph adenoma in older ones. Diagnostic evaluation must be stepwise and methodical, aimed at first confirming the presence of the disease, and then looking for the etiology.
openaire +3 more sources
Endogenous Cushing's Syndrome (CS) is a relatively uncommon disease in children. The etiology is more often a primary adrenal cause in infants and younger children, and corticotroph adenoma in older ones. Diagnostic evaluation must be stepwise and methodical, aimed at first confirming the presence of the disease, and then looking for the etiology.
openaire +3 more sources
New England Journal of Medicine, 1995
Cushing's syndrome is usually caused by the secretion of corticotropin or cortisol by a pituitary or adrenal tumor, respectively, or by ectopic secretion of corticotropin. It is possible to determine the specific abnormality in most patients, but it can sometimes be difficult to decide whether the patient has hypercortisolism and whether it is primary ...
openaire +3 more sources
Cushing's syndrome is usually caused by the secretion of corticotropin or cortisol by a pituitary or adrenal tumor, respectively, or by ectopic secretion of corticotropin. It is possible to determine the specific abnormality in most patients, but it can sometimes be difficult to decide whether the patient has hypercortisolism and whether it is primary ...
openaire +3 more sources
Pediatric Clinics of North America, 1990
The 10 years since this journal's last review of CS have seen extraordinary advances in our understanding of many aspects of its causes, diagnosis, and treatment. The spectrum of what are now called the Cushing syndromes has expanded considerably to include CD, multiple sources of ectopic ACTH secretion, and an apparent autoimmune cause.
openaire +3 more sources
The 10 years since this journal's last review of CS have seen extraordinary advances in our understanding of many aspects of its causes, diagnosis, and treatment. The spectrum of what are now called the Cushing syndromes has expanded considerably to include CD, multiple sources of ectopic ACTH secretion, and an apparent autoimmune cause.
openaire +3 more sources
Journal of Surgical Oncology, 2012
AbstractCushing's syndrome (CS) results from prolonged exposure to elevated endogenous cortisol. Majority of cases are caused by ACTH, pituitary, or ectopic origin. Primary adrenal hypersecretion is 15–20% caused by adenomas, carcinomas (ACC), and rarely by nodular adrenocortical disease. CS presents with all typical features.
openaire +3 more sources
AbstractCushing's syndrome (CS) results from prolonged exposure to elevated endogenous cortisol. Majority of cases are caused by ACTH, pituitary, or ectopic origin. Primary adrenal hypersecretion is 15–20% caused by adenomas, carcinomas (ACC), and rarely by nodular adrenocortical disease. CS presents with all typical features.
openaire +3 more sources
2020
Cushing’s syndrome is associated with significant morbidity and mortality and should be considered in specific clinical circumstances, including patients who show suggestive symptoms and signs or have incidental adrenal or pituitary lesions. Exogenous glucocorticoid use should always be thoroughly ascertained, as this is the most common cause of ...
Nicholas A. Tritos, Brandon P Galm
openaire +2 more sources
Cushing’s syndrome is associated with significant morbidity and mortality and should be considered in specific clinical circumstances, including patients who show suggestive symptoms and signs or have incidental adrenal or pituitary lesions. Exogenous glucocorticoid use should always be thoroughly ascertained, as this is the most common cause of ...
Nicholas A. Tritos, Brandon P Galm
openaire +2 more sources