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Hyperkortisolismus (Cushing-Syndrom, Morbus Cushing, adrenales Cushing-Syndrom)
2014Als Cushing-Syndrom bezeichnet man samtliche Zustande pathologisch erhohter und biologisch wirksamer Kortisolspiegel im Blut, einschlieslich medikamentos-induzierter Formen. Als Morbus Cushing wird die zentrale hypothalamisch-hypophysare Form des Hyperkortisolismus bei Hypophysenadenomen bezeichnet. Das adrenale Cushing-Syndrom ist sehr selten und kann
Felix Kawan, Paolo Fornara
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Nature Reviews Disease Primers
Cushing syndrome (CS) is a constellation of signs and symptoms caused by excessive exposure to exogenous or endogenous glucocorticoid hormones. Endogenous CS is caused by increased cortisol production by one or both adrenal glands (adrenal CS) or by elevated adrenocorticotropic hormone (ACTH) secretion from a pituitary tumour (Cushing disease (CD)) or ...
Lynnette K. Nieman +6 more
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Cushing syndrome (CS) is a constellation of signs and symptoms caused by excessive exposure to exogenous or endogenous glucocorticoid hormones. Endogenous CS is caused by increased cortisol production by one or both adrenal glands (adrenal CS) or by elevated adrenocorticotropic hormone (ACTH) secretion from a pituitary tumour (Cushing disease (CD)) or ...
Lynnette K. Nieman +6 more
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Pituitary, 2004
Structural and functional impairment of skeletal system is a relevant cause of morbidity and disability in patients with Cushing's syndrome (CS). Approximately 30-50% of patients with CS experience fractures (particularly at the spinal level) consistent with the 50% incidence of osteoporosis.
MANCINI T +3 more
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Structural and functional impairment of skeletal system is a relevant cause of morbidity and disability in patients with Cushing's syndrome (CS). Approximately 30-50% of patients with CS experience fractures (particularly at the spinal level) consistent with the 50% incidence of osteoporosis.
MANCINI T +3 more
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2003
The period between the onset of the signs and symptoms of Cushing’s syndrome and its definitive diagnosis averages 5 yr (1). Thus, the idea of an early diagnosis is somewhat of an oxymoron. The diagnosis requires a convincing combination of clinical findings and biochemical abnormalities (2–8). The obvious combination is an established clinical picture
Cook Dm, Loriaux Dl
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The period between the onset of the signs and symptoms of Cushing’s syndrome and its definitive diagnosis averages 5 yr (1). Thus, the idea of an early diagnosis is somewhat of an oxymoron. The diagnosis requires a convincing combination of clinical findings and biochemical abnormalities (2–8). The obvious combination is an established clinical picture
Cook Dm, Loriaux Dl
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Androgens in Cushing’s Syndrome
2019Although polycystic ovary syndrome (PCOS) is the most common androgen excess disorder, screening for Cushing's Syndrome (CS) should be considered in women with PCOS phenotype, particularly if they are also affected by other disturbances that increase their pretest probability (e.g., osteoporosis/bone fractures).
Arnaldi G., Martino M.
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, 2011 SUBCLINICAL CUSHING'S SYNDROME
Endocrinology and Metabolism Clinics of North America, 2000Classic Cushing's syndrome is a rare disease with an estimated incidence of 1 case per 100,000 persons. With routine use of imaging techniques such as ultrasound and CT, adrenal masses are being detected with increased frequency. A substantial percentage of these incidentalomas are hormonally active, with 5% to 20% of the tumors producing ...
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