Results 81 to 90 of about 1,243,942 (199)

A closer look at Cushing's syndrome [PDF]

This infographic offers an insight into Cushing's Syndrome, with a focus on its primary causes, diagnostic tests, and treatment ...
Wisco, Jonathan J., Cengiz, Kayra
core   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

A Giant 5000 g Primary Adrenocortical Carcinoma: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Adrenocortical carcinoma (ACC) is an aggressive malignancy that may present without hormonal symptoms. A 64 years old woman with abdominal pain, weight loss, and anemia had a massive adrenal tumor that required complex surgery. ACC should be considered in large abdominal masses. Complete surgical resection is essential.
Sadin Zahra, Aghajanzadeh Manouchehr, Mohammad Reza Sadin, Dadashi Arsalan, Poorsafar Mahdi, Aghzadeh Zeynab, Khyabani Mahmood, Shafaghi Afshin   +7 more
wiley   +1 more source

Rapid Growth of Dermatofibrosarcoma Protuberans Associated with Bilateral Adrenalectomy for Cushing’s Syndrome

Case Reports in Dermatology, 2011
We describe a 50-year-old Japanese patient with dermatofibrosarcoma protuberans (DFSP) rapidly growing after bilateral adrenalectomy for Cushing’s syndrome that reduced the serum level of cortisol from 17.1 to 0.8 mg/dl.
Sadanori Furudate, Taku Fujimura, Akira Hashimoto, Setsuya Aiba   +3 more
doaj   +1 more source

Multiple Machine Learning Algorithms for Predicting Postoperative Residual Tumor in Pituitary Neuroendocrine Tumors

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
An explainable random forest–based machine learning model accurately predicted postoperative residual tumors in PitNETs, with tumor size and Knosp grade as major predictors, offering a web‐based tool for individualized surgical risk assessment and precision management.
Mingrui Li, Chenyang Zhao, Guodong Tang, Yang Li, Qing Liu   +4 more
wiley   +1 more source

Invasive fungal infections in endogenous Cushing’s syndrome

Infectious Disease Reports, 2010
Cushing’s syndrome is a condition characterized by elevated cortisol levels that can result from either augmented endogenous production or exogenous administration of corticosteroids.
Rafael Selbach Scheffel, José Miguel Dora, Letícia Schwerz Weinert, Valério Aquino, Ana Luiza Maia, Luis Henrique Canani, Luciano Z. Goldani   +6 more
doaj   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, Volume 34, Issue 11, Page 2051-2060, November 2026.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source

Iatrogenic Cushing's syndrome caused by intranasal steroid use

İstanbul Kuzey Klinikleri, 2017
Cushing's syndrome (CS) is common after oral steroid use and has also been reported following topical or inhaled use, but it is extremely uncommon after intranasal administration.
Fatma Dursun, Heves Kırmızıbekmez
doaj   +1 more source

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, Volume 300, Issue 5, Page 590-609, November 2026.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

New diagnostic tests for Cushing's syndrome: Uses of naloxone, vasopressin and alprazolam

, 1996
1. We set out to investigate whether the administration of naloxone alone, naloxone plus vasopressin (AVP) or naloxone plus alprazolam to patients with Cushing's syndrome would result in a blunted dynamic response of the pituitary-adrenal axis compared ...
Hockings, GI, Torpy, D. J., Torpy, DJ, GI Hockings, JE Grice, GV Crosbie, Hockings, G. I., Jackson, R. V., Walters, M. M., Crosbie, G. V., DJ Torpy, MM Walters, Strakosch, CR, Grice, JE, Grice, J. E., Walters, MM, Strakosch, C. R., Jackson, RV, RV Jackson, CR Strakosch, Crosbie, GV   +20 more
core   +1 more source