Results 91 to 100 of about 20,022 (229)
Introduction Adrenocorticotropic hormone-independent macronodular adrenal hyperplasia, characterized by bilateral macronodular adrenal hypertrophy and autonomous cortisol production, is a rare cause of Cushing’s syndrome.
Ito Toshiki +9 more
doaj +1 more source
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is associated with an increased risk of cerebrovascular disease, but the effects on cerebrovascular function are unknown. In this pilot study, we sought to compare cerebrovascular perfusion, pulsatility, reactivity and metabolism between women with PCOS and healthy volunteers using MRI, and ...
Melissa E. Wright +5 more
wiley +1 more source
We report here a pediatric patient whose Cushing's Disease was diagnosed late because of her cyclical presentation, presumably due to subclinical pituitary apoplexy.
Sara H. Rahman +5 more
doaj +1 more source
TRH: Pathophysiologic and clinical implications [PDF]
Thyrotropin releasing hormone is thought to be a tonic stimulator of the pituitary TSH secretion regulating the setpoint of the thyrotrophs to the suppressive effect of thyroid hormones. The peptide stimulates the release of normal and elevated prolactin.
A. Enjalbert +82 more
core +1 more source
Cushing’s disease, or pituitary ACTH dependent Cushing’s syndrome, is a rare disease responsible for increased morbidity and mortality. Signs and symptoms of hypercortisolism are usually non specific: obesity, signs of protein wasting, increased blood ...
Bernard Conte-Devolx +3 more
core +1 more source
Despite major advances in laboratory methods, radiology, and neurosurgery, the evaluation and therapy of Cushing’s syndrome remains a major challenge to clinicians. In a substantial percentage of the patients with Cushing’s syndrome, laboratory and radiologic studies yield data that are confusing or misleading.
openaire +2 more sources
The action of glucocorticoids is modulated by isoenzymes 11?-hidroxiesteróide desidrogenases (11?-HSD) type 1 and 2. The knowledge concerning these isoenzymes contribute to the understanding of the regulatory mechanisms involved in several disease ...
Maria Betânia Pereira Toralles +3 more
doaj +1 more source
Objectives: To illustrate that the protease inhibitor (PI) ritonavir, widely used as part of the treatment for HIV, might cause drug–drug interactions with inhaled corticosteroids. Material and methods: A case report is presented.
Imro Vlasveld +2 more
doaj +1 more source
Etomidate in the control of severe Cushing's syndrome by neuroendocrine carcinoma
Key Clinical Message Etomidate is a very effective drug in severe Cushing's syndrome that is refractory to ketoconazol. Control of the serum cortisol levels in ectopic Cushing's syndrome can be obtained with infusion rates much lower than those used in ...
Alfredo Adolfo Reza‐Albarrán +2 more
doaj +1 more source
Ectopic ACTH Production Leading to Diagnosis of Underlying Medullary Thyroid Carcinoma
Medullary thyroid carcinoma (MTC) has been described as a source of ectopic ACTH secretion in patients with Cushing’s syndrome. This is an infrequent association, occurring in less than 1% of MTC cases. Among these, it is even more unusual for an initial
Leslee N. Matheny MD +2 more
doaj +1 more source

