Results 31 to 40 of about 24,911 (211)
Loss-of-function mutations in the CABLES1 gene are a novel cause of Cushing's disease. [PDF]
The CABLES1 cell cycle regulator participates in the adrenal-pituitary negative feedback, and its expression is reduced in corticotropinomas, pituitary tumors with a largely unexplained genetic basis.
Assié, Guillaume +20 more
core +2 more sources
Cushing's Disease in Children: Report of Three Cases
Cushing's disease is rare in children and adolescents. We report the clinical presentations of three children with Cushing's disease. All three exhibited the typical symptoms and signs of weight gain and growth retardation.
Ping-Yi Hsu +6 more
doaj +1 more source
Background Cushing’s syndrome occurs due to overproduction of cortisol from adrenal glands. Endogenous hypercortisolemia can occur secondary to adrenocorticotropic hormone (ACTH) dependent as well as independent causes.
Piyumi Sachindra Alwis Wijewickrama +4 more
doaj +1 more source
The Pathophysiology and Treatment of Hypertension in Patients With Cushing's Syndrome [PDF]
When hypertension, a pathology that is frequently found in the general population, presents in a young patient, secondary causes such as Cushing's syndrome (CS), a rare disease characterized by long-term elevated cortisol levels, should be considered ...
Barbot, Mattia +2 more
core +1 more source
Osilodrostat‐induced adrenal insufficiency in a patient with Cushing's disease
Cushing's disease is a rare condition caused by a benign pituitary tumor underlying adrenocorticotropic hormone excess. Medical treatment is implemented when surgical resection is not curative.
Catherine Ekladios +3 more
doaj +1 more source
Introduction Cushing’s syndrome is a relatively rare condition that results from chronic hypercortisolism. This syndrome is characterized by the presence of various psychiatric manifestations that can accompany it at all its stages of evolution.
F. Z. Chamsi +3 more
doaj +1 more source
Measurement of late-night salivary cortisol with an automated immunoassay system [PDF]
Background: Measurement of late-night salivary cortisol concentrations is increasingly used as a screening test in suspected Cushing's syndrome. Cortisol concentrations are typically extremely low in late-night samples and discordant assay-specific ...
Arnaldi +19 more
core +1 more source
Effect of sampling method and storage conditions on albumin, retinol-binding protein, and N-acetyl-β-D-glucosaminidase concentrations in canine urine samples [PDF]
Urinary markers for renal dysfunction are gaining interest but effects of sampling method, storage conditions, and urinary tract inflammation or infection on these markers are unclear Therefore, the objectives of the current study were to determine the ...
Daminet, Sylvie +4 more
core +1 more source
Severe Cushing’s syndrome and bilateral pulmonary nodules: beyond ectopic ACTH
Cushing’s syndrome is a rare disease that results from prolonged exposure to supraphysiological levels of glucocorticoids. Severe and rapidly progressive cases are often, but not exclusively, attributable to ectopic ACTH secretion.
Carlos Tavares Bello +2 more
doaj +1 more source
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi +4 more
wiley +1 more source

