Results 41 to 50 of about 24,911 (211)

Medical treatment of Cushing's syndrome: Adrenal-blocking drugs and ketaconazole [PDF]

, 2010
Cushing's syndrome is associated with serious morbidity and increased mortality. Irrespective of its cause, i.e. a pituitary adenoma, ectopic ACTH production or an adrenal neoplasia, Cushing's syndrome is primarily treated surgically.
Feelders, R.A. (Richard), Herder, W.W. (Wouter) de, Hofland, L.J. (Leo)   +2 more
core   +13 more sources

High recovery rate of adrenal function after successful surgical treatment of Cushing’s syndrome

Endocrine Connections
Context: Successful first-line treatment of Cushing’s syndrome by resection of the underlying tumor is usually followed by adrenal insufficiency. Purpose: The aims of this study were to determine the recovery rate and time to recovery of adrenal function
Annenienke C van de Ven, Pepijn van Houten, Lisan Grevers, Henri J L M Timmers, Erik van Lindert, Johan F Langenhuijsen, Romana T Netea-Maier   +6 more
doaj   +1 more source

DIAGNOSIS OF CUSHING’S SYNDROME; BIOCHEMICAL INVESTIGATIONS

Journal of Cancer and Allied Specialties, 2018
Cushing’s syndrome remains an uncommon diagnosis with majority of non-specific and few specific clinical features suggestive of the condition. Results of biochemical investigations are often affected by confounding factors making diagnosis of Cushing’s ...
Ahmed Imran Siddiqi, Muhammad Usamah Bin Noor   +1 more
doaj   +1 more source

Molecular Mechanisms of Glucocorticoid Resistance in Corticotropinomas: New Developments and Drug Targets

Frontiers in Endocrinology, 2020
Cushing's disease is characterized by excessive adrenocorticotropin hormone (ACTH) secretion caused by a corticotroph tumor of the pituitary gland, leading to hypercortisolism and increased morbidity and mortality. The molecular causes of the disease are
Denis Ciato, Adriana Albani
doaj   +1 more source

Resistant arterial hypertension in a patient with adrenal incidentaloma multiple steno-obstructive vascular lesions and antiphospholipid syndrome [PDF]

, 2015
Resistant hypertension is defined as above of blood pressure (≤ 140/90 mmHg) despite therapy with three or more antihypertensive drugs of different classes at maximum tolerable doses with one bling a diuretic.
CONCISTRE, ANTONIO, Gambale, G., IANNUCCI, Gino, Letizia, C., MARINELLI, CRISTIANO, PETRAMALA, LUIGI, Toma, G. De, Vincentis, G. De, ZACCARIA, Alvaro   +8 more
core  

A case report: retigabine induced oral mucosal dyspigmentation of the hard palate [PDF]

, 2015
Background Dyspigmentation of the oral mucosa has a multitude of aetiological causes. Retigabine, a new antiepileptic drug, has the potential side effect of inducing a blue/purple pigmentation of the oral mucosa in addition to the skin, lips, nails and ...
Beacher, Nicholas G., Brodie, Martin J., Goodall, Christine   +2 more
core   +1 more source

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome

Advanced Science, EarlyView.
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao, Chuyu Yun, Hongying Shan, Yuqian Wang, Xiunan Chen, Weisi Lian, Tianliu Peng, Min Zhao, Xunsi Qin, Kailun Hu, Ping Zhou, Yue Wang, Yanli Pang, Rong Li   +13 more
wiley   +1 more source

Usefulness of desmopressin testing to predict relapse during long-term follow-up in patients in remission from Cushing’s disease

Endocrine Connections, 2017
Recurrence of Cushing’s disease after successful transsphenoidal surgery occurs in some 30% of the patients and the response to desmopressin shortly after surgery has been proposed as a marker for disease recurrence.
Alberto Giacinto Ambrogio, Massimiliano Andrioli, Martina De Martin, Francesco Cavagnini, Francesca Pecori Giraldi   +4 more
doaj   +1 more source

DYNAMICS OF PSYCHIATRIC SYMPTOMS IN CUSHING’S SYNDROME [PDF]

Journal of IMAB, 2020
Cushing’s syndrome may present with various psychiatric disorders which can lead to a misdiagnosis at the beginning, deterioration of the course of the disease and life-threatening complications.
Tatyana Telbizova, Ivan Aleksandrov, Mariana Arnaoudova   +2 more
doaj   +1 more source

Hyperglycemia induced by pasireotide in patients with Cushing’s disease or acromegaly [PDF]

, 2016
PURPOSE: Cushing’s disease (CD) and acromegaly are characterized by excessive hormone secretion resulting in comorbidities such as impaired glucose metabolism, diabetes and hypertension.
Silverstein, Julie M
core   +2 more sources